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Faulhammer et al. found that Sac1p localized to the ER during exponential growth and was retained there by a direct interaction with an integral ER membrane protein called dolichol phosphate mannose synthase, or Dpm1p. When the researchers transferred these fast growing cells to nutrient-poor media, Sac1p moved to the Golgi within minutes./ W: Y7 y* P3 s
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Rbiya S. Tuma; D& i: h: O' v" ^' x
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rabiya@nasw.org! |& f% S$ Q4 h3 i6 p, B9 F
* ?% B& |3 O: r2 w! T2 FFrank Faulhammer, Gerlinde Konrad, Ben Brankatschk, Sabina Tahirovic, Andreas Kn?dler, and Peter Mayinger5 E: ]; W% y( L9 V" @
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J. Cell Biol. 2005 168: 185-191.(The lipid phosphatase Sac1p inhibits tra) |
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发表于 2009-3-6 08:45
发表于 2015-5-30 10:27
