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本帖最后由 aspen 于 2009-8-31 09:53 编辑
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Anthony DeFranco
. g; ~/ ?" K& t( L3 A% s( iDepartment of Microbiology & Immunology, University of California at San Francisco
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4 a$ H) W z, o3 K; e; @3 RThemes include:
$ q& l8 I( C8 K" j' G1. Checkpoints in B cell development: feedback from Ig gene rearrangements
) \6 `! \9 q4 B0 \3 [2. Stromal environment/growth factors for B cell development
+ P2 S: x p8 i r9 l. h2 y3. Lineage commitment: transcription factors and Notch signaling3 P# k! S3 u0 S! \# V& V& F, Z9 }
4. Central tolerance of B cells
" W' ^3 r; N- [" _6 ?' x5. Peripheral tolerance of B cells3 s$ i9 |, V9 f7 s; c$ X, X& p6 ^: E- m
6. 3 different types of mature B cells: choice of cell fate and relative roles |
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