PPT:Themes in B cell development (UCSF)

aspen

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( X8 \# y! ~4 Y- Q. ZAnthony DeFranco6 n8 z) ^0 x& T
Department of Microbiology & Immunology, University of California at San Francisco
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Themes include:4 H1 n4 X3 i+ f/ m! r) f
1. Checkpoints in B cell development:  feedback from Ig gene rearrangements7 i4 l4 ]( b, M; E3 S8 D9 ^' ~
2. Stromal environment/growth factors for B cell development) g; O' K( I. l* `" o  M
3. Lineage commitment:  transcription factors and Notch signaling
9 R, q2 B% [, |, Z+ e( |4. Central tolerance of B cells* t+ }- {5 L; d6 L# f
5. Peripheral tolerance of B cells
+ k' N0 ~# N1 t# S0 C0 @6 I0 d6. 3 different types of mature B cells: choice of cell fate and relative roles

hualin840518

thanks

hughliang

非常感谢！5 a6 }( k) y3 T) V- S# w

rainsky1314

thanks very much !

刘子文

谢谢

beidouhan

好东西呢