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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑
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经典高引用次数专著,很多要用到microarray分析技术的朋友可以参看下。
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在拿到你的microarray数据后,不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的 : L: ?1 D) ^0 b* z1 p$ G( C
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"This book should be required reading for any (future and present) post-genomic researcher..."
/ R d- s2 F$ `; n; T— Sean D. Mooney, Briefings in Bioinformatics
! _. o$ I1 G: ^& e, n9 ZProduct Description2 H' X8 ]; _3 y# t
Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.
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/ g% u& L0 |# y3 H9 CProduct Details
- {9 C. B, R% r; g3 |Hardcover: 326 pages % b+ E5 y5 e7 X" `" u- Z+ l( i
Publisher: The MIT Press; 1 edition (August 21, 2002)
8 B2 x, g( N! B) hLanguage: English
5 ]0 n0 q# u% U, V8 ~1 j/ q7 SISBN-10: 026211271X
/ u, f; P. w) B' sISBN-13: 978-0262112710
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Introduction
1 \$ E4 k, z( M介绍请参见Amazon9 ]& N- o, Z8 k# ^) t8 `
http://www.amazon.com/Microarray ... cular/dp/026211271X% w; @: j/ y9 `8 k: d' ~& \ A
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