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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑
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经典高引用次数专著，很多要用到microarray分析技术的朋友可以参看下。
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在拿到你的microarray数据后，不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的
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; |+ ~8 m W: [8 w5 o' U# EEditorial Reviews
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; e" Z# Y2 s+ l: y; M"This book should be required reading for any (future and present) post-genomic researcher..."" W. t( A. i" o" W1 z+ X
— Sean D. Mooney, Briefings in Bioinformatics
5 T7 r5 g1 R& H; v; K3 ?Product Description
( E P. e0 W5 qFunctional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.
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# g: |7 r0 V2 c% J( oProduct Details: X4 z" p) m( p& p9 L, M4 @
Hardcover: 326 pages
9 t0 e- D2 t- `2 t, KPublisher: The MIT Press; 1 edition (August 21, 2002)
8 L- c4 W6 ` W9 P }4 a1 MLanguage: English
' j& }2 Z: A% o$ t$ d$ r- {ISBN-10: 026211271X ; Z/ N# Y0 J# _& v: f2 J
ISBN-13: 978-0262112710
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Introduction# m4 m; P5 E1 s! K5 `
介绍请参见Amazon4 x6 |5 @+ ]5 X+ j
http://www.amazon.com/Microarray ... cular/dp/026211271X# }/ c" S; K5 o6 r( Y
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发表于 2010-5-20 18:48
发表于 2010-5-21 13:26
