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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑 . k* W/ N- o# }) a/ J/ F% c
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经典高引用次数专著,很多要用到microarray分析技术的朋友可以参看下。
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在拿到你的microarray数据后,不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的 ; f7 r. F# t6 E0 O1 O) J8 s
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Editorial Reviews
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"This book should be required reading for any (future and present) post-genomic researcher..."" i4 O* M) |# {' c
— Sean D. Mooney, Briefings in Bioinformatics ! I- [1 u" \5 K
Product Description
/ I2 @# U& F. Y4 S, eFunctional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.8 T* V' a' d& a& a* ?6 e- d+ \; H) O
: Z$ T/ {- _/ a( i7 UProduct Details
' y8 ~# V* p0 m# JHardcover: 326 pages . g3 W/ d" Y6 p2 S0 N+ X$ L( b
Publisher: The MIT Press; 1 edition (August 21, 2002)
( ^5 H* b- C+ T# O* B4 B3 CLanguage: English & o: a F6 t! N
ISBN-10: 026211271X
! H; v% V0 Y% W, }2 ~+ a7 nISBN-13: 978-0262112710
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Introduction8 t7 j1 e$ B, b7 p4 A
介绍请参见Amazon6 W6 t9 p" }8 k8 `+ b
http://www.amazon.com/Microarray ... cular/dp/026211271X8 |" m8 c/ }1 ]4 u# Q7 x# l# z2 a, ?
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