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本帖最后由 细胞海洋 于 2010-8-26 06:43 编辑 ( X7 x3 l- S5 y
) s3 ^6 {% x6 ~心脏心包及窦状角的的发育有赖于来自间充质的心外膜的扩增，而Wt1和维甲酸信号通路参与了这个过程/ }, X5 P" X7 N( \6 M9 B
Wt1 and Retinoic Acid Signaling in the Subcoelomic Mesenchyme Control the Development of the Pleuropericardial Membranes and the Sinus Horns( m7 K' Y7 U4 ~- W2 }$ o8 k6 J
Pericardium and sinus horn formation are coupled and depend on the expansion and correct temporal
2 R9 [& i4 l* c1 \+ L) ~2 X& orelease of pleuropericardial membranes from the underlying subcoelomic mesenchyme. Wt1 and downstream
; q+ H1 i: p6 W, x* x4 Y& t" DRaldh2/retinoic acid signaling are crucial regulators of this process. Thus, our results provide novel insight into
i* |/ r7 r v# T1 mthe genetic and cellular pathways regulating the posterior extension of the mammalian heart and the formation
; f! B* E* e7 a0 g y7 Fof its coelomic lining |
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发表于 2010-8-26 00:09
兄弟妳在狂看文献啊
