Circ. Res：Wt1和维甲酸信号通路参与心脏心包及窦状角的的发育

zhangjinxy

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) p% s9 X6 Z& t7 P1 k, U6 C' }2 @心脏心包及窦状角的的发育有赖于来自间充质的心外膜的扩增，而Wt1和维甲酸信号通路参与了这个过程
$ @6 r5 J% l" \8 s8 f6 h+ C5 f! UWt1 and Retinoic Acid Signaling in the Subcoelomic Mesenchyme Control the Development of the Pleuropericardial Membranes and the Sinus Horns$ X) D4 j; \$ S  q: s
          Pericardium and sinus horn formation are coupled and depend on the expansion and correct temporal
$ G8 @# u! t2 l% orelease of pleuropericardial membranes from the underlying subcoelomic mesenchyme. Wt1 and downstream
0 }3 [  G5 i) jRaldh2/retinoic acid signaling are crucial regulators of this process. Thus, our results provide novel insight into; K! x+ i; b% ]
the genetic and cellular pathways regulating the posterior extension of the mammalian heart and the formation9 _7 R$ w# y' T0 |' X3 V
of its coelomic lining

xuhuanyu

兄弟妳在狂看文献啊