iPS与疾病模型的12篇文章！

linlicau

分化但未观察到疾病表型的：
0 N0 Z/ V+ K+ V) n1.        Dimos, J.T. et al. Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons. Science 321, 1218-1221 (2008).$ U" e- l3 P+ b8 g, I* x
神经疾病：
9 L( }  U; T% b4 f) y3 Y2.        Park, I.-H. et al. Disease-Specific Induced Pluripotent Stem Cells. Cell 134, 877-886 (2008).
; R6 X3 I. F* n. Q: c; Q神经疾病：
% S# l2 H1 z( N4 c3.        Soldner, F. et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell 136, 964-977 (2009).
" e3 L2 Y; x% O神经疾病：
3 M2 C$ F5 @7 t4.        Maehr, R. et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proceedings of the National Academy of Sciences 106, 15768-15773 (2009).
, D9 W' Q1 K5 `3 I糖尿病：
* W( g- |3 n/ f* t5.        Ye, Z. et al. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114, 5473-5480 (2009).
/ ~0 v# h3 _& y4 K* |5 q/ Q3 Z血液疾病：
8 g  Q& u/ _+ J: p5 R$ w6.     Yang, J. et al. Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader-Willi syndrome. Journal of Biological Chemistry.
9 W' ~. w5 X  X- O, g* U  Egenomic imprinting disorder：$ [* i5 j9 t) N
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成功观察到疾病细胞表型的：! P( [/ H* P  k; z4 `
7.        Ebert, A.D. et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-280 (2009).
4 Y6 h. |4 Z3 F' m* |: ~4 H, B神经疾病：" l, Q% @9 @  k/ z1 n
8.        Lee, G. et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461, 402-406 (2009).: o2 O1 Z$ B" [8 R5 N) I2 O8 f
神经疾病：! F. I  h& m6 D) o2 O% f
9.        Raya, A. et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460, 53-59 (2009).
! h* R+ ]+ Y& x$ Z6 E7 `血液疾病：7 |8 x" f5 X2 j# A; N
10.        Rashid, S.T. et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. The Journal of Clinical Investigation 120, 3127-3136 (2010).) @9 o& M1 l& \; m4 V
肝脏疾病：1 G5 f; M2 E# n) |: y7 Q
11.        Moretti, A. et al. Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome. New England Journal of Medicine 363, 1397-1409 (2010).
" A- D' x/ W  U心脏疾病：$ J7 S  t2 n. z  p
12.        Ghodsizadeh, A. et al. Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells. Stem Cell Reviews and Reports 6, 622-632 (2010).! O) C  h; e* \2 q$ ]5 J
肝脏疾病：
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# }& p9 Z  U/ U( c; w3 M3 G望细胞海洋多加威望和包包啊~

mayansen1314

看看是啥

fjnuxp

非常好的资料、、

基拉

全部收了

苏眉1989

文章很好很强大就是太多了，还是英文的，呜呜

苏眉1989

真的找到了。谢谢你们

艾心痕

谢谢，感激涕零！

jane1lee

谢谢分享，很好，很强大！！！

大笨鸟

谢谢分享

marrowstem

极好资料，谢谢分享。