求助 关于NKT细胞 Nature review of immunology 文献一篇

woosheng

Nature Reviews Immunology 9,         28–38         (1 January 2009) 7 P/ S* n8 v) B( Z9 X
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Harnessing invariant NKT cells in vaccination strategies
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) k. ~2 u& E* w  F, V' V4 F+ W: EVincenzo Cerundolo , Jonathan D. Silk , S. Hajar Masri & Mariolina Salio
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  U4 O4 a; L" }4 G! E: wTo optimize vaccination strategies, it is important to use protocols that can 'jump-start' immune responses by harnessing cells of the innate immune system to assist the expansion of antigen-specific B and T cells. In this Review, we discuss the evidence indicating that invariant natural killer T (iNKT) cells can positively modulate dendritic cells and B cells, and that their pharmacological activation in the presence of antigenic proteins can enhance antigen-specific B- and T-cell responses. In addition, we describe structural and kinetic analyses that assist in the design of optimal iNKT-cell agonists that could be used in the clinical setting as vaccine adjuvants.

tonley

都中级会员了，还不知道怎么求助，你发摘要有什么用，发个链接啊，难道还要应助的人现去pubmed 或 isiknowledge 检索？

hstudent

okok

woosheng

回复 2# tonley 1 P, _3 j: O1 K* G7 w# B

6 g  E1 f1 {6 p/ R0 h8 l谢谢你的提醒，
3 ?  ]8 [  K8 S* F, s我发文摘的理由是，其他网友也可能对此文献感兴趣。