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肝细胞 hepatocytes
' k* P: U$ z' Z0 H6 C9 W7 F1 Rashid, S.T. et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. The Journal of Clinical Investigation 120, 3127-3136 (2010).
' s. x1 N" U( S' G2 Ghodsizadeh, A. et al. Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells. Stem Cell Reviews and Reports 6, 622-632 (2010).
: `$ L! O5 B3 w `& F1 i: |3 Sullivan, G.J. et al. Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology 51, 329-335 (2010).
( [/ P! Q& x: e: A8 R" Z0 a& l4 Si-Tayeb, K. et al. Highly efficient generation of human hepatocyte–like cells from induced pluripotent stem cells. Hepatology 51, 297-305 (2010).
. \+ r2 H% D [% g# O7 c' O& J5 Song, Z. et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res 19, 1233-1242 (2009).
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8 K! t0 {& H+ b7 J. j0 T5 `0 X1 }4 P神经细胞, X3 g6 L5 a; \6 G' r) n
neural crest precusors. _4 T1 Y' k4 w4 o# X
6 Lee, G. et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461, 402-406 (2009). / x4 _2 J0 }- D& h/ I
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neuroepithelial cell
. f1 U, X1 H7 U- c4 x2 C) M9 E7 Hu, B.-Y. et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proceedings of the National Academy of Sciences 107, 4335-4340 (2010) 9 M* r& W% G! O( @8 n& H
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motor neurons【包括文献7】
& R& E3 W* u* j: C8 Dimos, J.T. et al. Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons. Science 321, 1218-1221 (2008).! j1 |. d& r6 Y) i
9 Ebert, A.D. et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-280 (2009). 6 V; \9 t- p- p
10 Chambers, S.M. et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotech 27, 275-280 (2009).
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dopaminergic neurons of the midbrain 【包括文献10】8 P% ?6 O$ c( B
11 Soldner, F. et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell 136, 964-977 (2009).
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glia 【包括文献7,8】
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# l/ I/ i" A# ~+ E# m. u1 z7 t7 [视网膜细胞
9 P# i' G4 [; z. |Retinal Pigmented Epithelium
* u: t5 ?( }# k9 o7 O# D12 Buchholz, D.E. et al. Derivation of Functional Retinal Pigmented Epithelium from Induced Pluripotent Stem Cells. Stem Cells 27, 2427-2434 (2009).
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retinal cells1 |# \$ K9 g4 u8 B; g, N& D9 j
13 Osakada, F. et al. In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci 122, 3169-3179 (2009)., d: Z H. T% X5 I7 F" J+ V
14 Meyer, J.S. et al. Modeling early retinal development with human embryonic and induced pluripotent stem cells. Proceedings of the National Academy of Sciences 106, 16698-16703 (2009).
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& R- p: }5 e8 a2 J2 z% ]( ]心肌细胞 cardiomyocytes( j9 O; k* z2 W7 d l2 W8 `
15 Moretti, A. et al. Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome. New England Journal of Medicine 363, 1397-1409 (2010).& m, u$ Y+ A9 X- [4 A
16 Carvajal-Vergara, X. et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 465, 808-812 (2010).% ?* Z) }6 Q- |
17 Zhang, J. et al. Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells. Circ Res 104, e30-41 (2009).* y) R% s* G* U% U# i
18 Zwi, L. et al. Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells. Circulation 120, 1513-1523 (2009).
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# A9 B& X: a2 M6 `% b! D, {, c血管和血液相关细胞
8 I; P: _; i4 g* P$ Zhaematopoietic progenitors
8 {; h7 P1 b- N& Y7 N3 L. N19 Ye, Z. et al. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114, 5473-5480 (2009).
4 k" V2 @- b3 b# E20 Raya, A. et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460, 53-59 (2009).0 y- ]" t3 H) f" }6 w
7 m: }# b0 ^. T; V1 K. T- B" `$ \blood cells
( m K; P5 b i+ Q6 M, J% `0 T& b/ C7 L21 Choi, K.-D. et al. Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells. Stem Cells 27, 559-567 (2009).
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. Q# x2 i9 ^. \( [2 fvascular endothelial cells【包括文献21】' j5 @* d- ^. S, f. w( Q
22 Feng, Q. et al. Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence. Stem Cells 28, 704-712 (2010).: N1 [ J! K3 Q% ^- \0 d/ l3 L
23 Taura, D. et al. Induction and Isolation of Vascular Cells From Human Induced Pluripotent Stem Cells--Brief Report. Arterioscler Thromb Vasc Biol 29, 1100-1103 (2009).0 t1 O+ V: h9 J! v, B
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胰岛素产生细胞 insulin-producing cells
6 y7 H% e; v3 H+ T- {* C24 Maehr, R. et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proceedings of the National Academy of Sciences 106, 15768-15773 (2009).3 ~ w# N( O- }2 @2 P, r" ?2 `% u
25 Zhang, D. et al. Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res 19, 429-438 (2009).
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: J0 f, `! y! Y3 m5 s原生殖细胞 primordial germ cells! o5 N) g( m7 A" p6 \' R, b; S
26 Park, T.S. et al. Derivation of Primordial Germ Cells from Human Embryonic and Induced Pluripotent Stem Cells Is Significantly Improved by Coculture with Human Fetal Gonadal Cells. Stem Cells 27, 783-795 (2009).2 w& N# @; f% j$ }
( V' H6 I ^4 _* A脂肪细胞 adipocyte2 ]5 r Z( L# b. l
27 Taura, D. et al. Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells. FEBS Letters 583, 1029-1033 (2009).- Q$ J) l% n8 A7 I N4 k! i: \
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可能会有失误的地方,见谅!
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