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肝细胞 hepatocytes
) t# w* ? A: M6 d1 N1 Rashid, S.T. et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. The Journal of Clinical Investigation 120, 3127-3136 (2010). : ^2 D' M% i$ Y2 \
2 Ghodsizadeh, A. et al. Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells. Stem Cell Reviews and Reports 6, 622-632 (2010). . r& N6 A# W6 [8 H! Y
3 Sullivan, G.J. et al. Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology 51, 329-335 (2010).
% h; ?4 b. n% e: a5 ?9 Y" e+ p' x4 Si-Tayeb, K. et al. Highly efficient generation of human hepatocyte–like cells from induced pluripotent stem cells. Hepatology 51, 297-305 (2010).. M1 N; x0 G+ A$ V3 W) p
5 Song, Z. et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res 19, 1233-1242 (2009).
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神经细胞
& C( ?! Y7 s5 g- Rneural crest precusors$ e7 y# \; W$ @+ D. |
6 Lee, G. et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461, 402-406 (2009). 6 f0 O& ?$ |6 q4 ?4 T
3 T" z7 L& n9 }. ^$ hneuroepithelial cell) Y1 a3 h/ _6 w+ u
7 Hu, B.-Y. et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proceedings of the National Academy of Sciences 107, 4335-4340 (2010)
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motor neurons【包括文献7】
1 f1 a8 i5 n" G" E0 e& x) B7 {7 \8 Dimos, J.T. et al. Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons. Science 321, 1218-1221 (2008).: Q2 u8 Y! j: T" g
9 Ebert, A.D. et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-280 (2009). 3 U" y- n2 J2 d, |
10 Chambers, S.M. et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotech 27, 275-280 (2009). , g+ z$ c' |9 w$ l; \ i. j
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dopaminergic neurons of the midbrain 【包括文献10】
5 T( b0 |( U- p/ r' L; J11 Soldner, F. et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell 136, 964-977 (2009).
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+ W1 ~4 b7 v* e( v- bglia 【包括文献7,8】# m0 n2 _$ L/ D; Y
: P! w" W/ T* L- H9 z7 I' y, T5 h- h+ U视网膜细胞
5 H3 ^& z7 @: F9 ^% t& KRetinal Pigmented Epithelium
5 _8 E4 q' g0 X1 S- H) w12 Buchholz, D.E. et al. Derivation of Functional Retinal Pigmented Epithelium from Induced Pluripotent Stem Cells. Stem Cells 27, 2427-2434 (2009).
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. i0 @, ^# Q5 A5 R, U. gretinal cells
1 A: ~! N7 T% ~ w( \( ~7 Q2 ^13 Osakada, F. et al. In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci 122, 3169-3179 (2009).- V7 y- r! \; O; e
14 Meyer, J.S. et al. Modeling early retinal development with human embryonic and induced pluripotent stem cells. Proceedings of the National Academy of Sciences 106, 16698-16703 (2009).
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1 D8 J6 @6 S4 I' F2 `心肌细胞 cardiomyocytes
! m$ C. z& \( J+ Y15 Moretti, A. et al. Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome. New England Journal of Medicine 363, 1397-1409 (2010)." j4 m/ c6 f- ] m( `+ P
16 Carvajal-Vergara, X. et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 465, 808-812 (2010).
* d% e) U) m5 m# j# n( E9 v17 Zhang, J. et al. Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells. Circ Res 104, e30-41 (2009). Z, e+ m6 J; }4 K8 m( a
18 Zwi, L. et al. Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells. Circulation 120, 1513-1523 (2009).( r0 A% N* V: l. v: O
U( r* M: N. ?血管和血液相关细胞
7 l& W- k0 z+ n& F- yhaematopoietic progenitors/ _1 Q$ ~2 D$ H3 }
19 Ye, Z. et al. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114, 5473-5480 (2009).6 N* {5 A" ^; A* X1 j8 ]+ j$ N5 r
20 Raya, A. et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460, 53-59 (2009).0 ~" y7 R5 @# ^3 ^# U
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blood cells( b% Z% T$ H3 P2 I' U
21 Choi, K.-D. et al. Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells. Stem Cells 27, 559-567 (2009)./ h$ I2 H( E0 c# Y; U& i/ W3 S
5 D. E6 B' n2 ?: |3 Xvascular endothelial cells【包括文献21】
7 t/ {5 i7 Q7 { o* _22 Feng, Q. et al. Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence. Stem Cells 28, 704-712 (2010).+ o4 z5 b: S, o& ~9 u5 C
23 Taura, D. et al. Induction and Isolation of Vascular Cells From Human Induced Pluripotent Stem Cells--Brief Report. Arterioscler Thromb Vasc Biol 29, 1100-1103 (2009).
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胰岛素产生细胞 insulin-producing cells& ~5 b+ U0 q; S) V* S
24 Maehr, R. et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proceedings of the National Academy of Sciences 106, 15768-15773 (2009).) A- ^! q) |% A: \3 g' b0 W: t
25 Zhang, D. et al. Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res 19, 429-438 (2009).
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原生殖细胞 primordial germ cells
* `8 i: e: D7 n' [! \26 Park, T.S. et al. Derivation of Primordial Germ Cells from Human Embryonic and Induced Pluripotent Stem Cells Is Significantly Improved by Coculture with Human Fetal Gonadal Cells. Stem Cells 27, 783-795 (2009).# h0 k- c0 }- {9 Q) t3 E- R+ z
+ z9 y+ u R: R' k5 q7 ^脂肪细胞 adipocyte; j$ z9 L# m* _1 y l
27 Taura, D. et al. Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells. FEBS Letters 583, 1029-1033 (2009).3 E5 ]! O8 t3 x# Q/ P
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可能会有失误的地方,见谅!
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