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肝细胞 hepatocytes/ F/ z( v+ f7 t- u
1 Rashid, S.T. et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. The Journal of Clinical Investigation 120, 3127-3136 (2010).
- a- c0 n2 N- c1 {/ j2 Ghodsizadeh, A. et al. Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells. Stem Cell Reviews and Reports 6, 622-632 (2010).
$ d; ^8 q$ d4 y0 b3 Sullivan, G.J. et al. Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology 51, 329-335 (2010).
8 ?& o( ]5 x5 }/ q c( n) x4 Si-Tayeb, K. et al. Highly efficient generation of human hepatocyte–like cells from induced pluripotent stem cells. Hepatology 51, 297-305 (2010).
# Q2 [# Y6 y, [% c$ g# B5 d5 Song, Z. et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res 19, 1233-1242 (2009).3 k1 h) D' b. E2 E# S
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神经细胞
' U4 G H% t4 X5 _neural crest precusors4 t, S8 b8 K" `8 P" {( c) d
6 Lee, G. et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461, 402-406 (2009).
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neuroepithelial cell
3 w) {1 w- x4 E/ l7 Hu, B.-Y. et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proceedings of the National Academy of Sciences 107, 4335-4340 (2010)
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& L+ Q; |& c+ b% m3 Jmotor neurons【包括文献7】0 g J; M6 G, e' g d0 @4 Q# T
8 Dimos, J.T. et al. Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons. Science 321, 1218-1221 (2008).
6 B" C" x: L. m$ e9 Ebert, A.D. et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-280 (2009). 0 \! G; b3 p0 B4 z6 T7 q; j
10 Chambers, S.M. et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotech 27, 275-280 (2009).
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dopaminergic neurons of the midbrain 【包括文献10】
1 Q. c, N2 `3 B" V) }* y; a, e11 Soldner, F. et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell 136, 964-977 (2009).
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/ Q, l1 J: I. x2 V+ ^+ }1 G Uglia 【包括文献7,8】
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! L3 T4 C3 Y( ~9 |' v+ A# E5 K. z视网膜细胞
; w6 y" A$ e: T( I/ N9 @# xRetinal Pigmented Epithelium1 U; Z: B) E4 A$ h3 S- ~/ s
12 Buchholz, D.E. et al. Derivation of Functional Retinal Pigmented Epithelium from Induced Pluripotent Stem Cells. Stem Cells 27, 2427-2434 (2009).3 L) ~$ P/ l8 z
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retinal cells7 I' _% S; N- n5 c
13 Osakada, F. et al. In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci 122, 3169-3179 (2009).6 u' ]( a1 I$ |4 m" c
14 Meyer, J.S. et al. Modeling early retinal development with human embryonic and induced pluripotent stem cells. Proceedings of the National Academy of Sciences 106, 16698-16703 (2009).
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+ E+ |" w2 o8 G, y. z心肌细胞 cardiomyocytes
w7 G: o% ]* v15 Moretti, A. et al. Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome. New England Journal of Medicine 363, 1397-1409 (2010).4 O* ~+ B; ]$ g7 O- P
16 Carvajal-Vergara, X. et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 465, 808-812 (2010).
1 y c9 i8 y9 @8 ]# U17 Zhang, J. et al. Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells. Circ Res 104, e30-41 (2009).2 r& D" \$ H. W3 B* f) c
18 Zwi, L. et al. Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells. Circulation 120, 1513-1523 (2009).* H7 G: h8 n! ?& K7 L. l7 \
* g S/ s- E; I7 T血管和血液相关细胞; Z, O- O2 ^, d6 @1 s& _* p
haematopoietic progenitors
7 H G" }8 M! \8 g19 Ye, Z. et al. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114, 5473-5480 (2009).6 j9 k5 b2 F' _2 c, n
20 Raya, A. et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460, 53-59 (2009).
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9 S( C' q0 O& }/ Q$ [+ \5 Dblood cells
' v I' x2 O2 j4 Z: {! a21 Choi, K.-D. et al. Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells. Stem Cells 27, 559-567 (2009).
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vascular endothelial cells【包括文献21】' G& y$ H% y2 s( m
22 Feng, Q. et al. Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence. Stem Cells 28, 704-712 (2010).* c: t' y# ?' q
23 Taura, D. et al. Induction and Isolation of Vascular Cells From Human Induced Pluripotent Stem Cells--Brief Report. Arterioscler Thromb Vasc Biol 29, 1100-1103 (2009). g$ S9 @' ?- b# I' _
, Y" N6 j8 `! C( u& J8 }1 H) A V胰岛素产生细胞 insulin-producing cells0 f# _- p! m9 s0 E- }8 M
24 Maehr, R. et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proceedings of the National Academy of Sciences 106, 15768-15773 (2009).( w0 N% R% k$ O: f, C; r
25 Zhang, D. et al. Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res 19, 429-438 (2009).$ C- i+ K+ r/ X& b6 c, a; P
* K) N: ] S( z% z: N5 E1 \, r原生殖细胞 primordial germ cells" |6 J! d5 s+ q' |
26 Park, T.S. et al. Derivation of Primordial Germ Cells from Human Embryonic and Induced Pluripotent Stem Cells Is Significantly Improved by Coculture with Human Fetal Gonadal Cells. Stem Cells 27, 783-795 (2009).% |4 _; m( \4 N5 U6 ~
2 O% R- J" h1 w5 z脂肪细胞 adipocyte
$ A) |$ v. B. U1 t9 m27 Taura, D. et al. Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells. FEBS Letters 583, 1029-1033 (2009).. x- ^% j+ Y/ V" N& t
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- _- C8 C2 F9 c2 a. I3 |可能会有失误的地方,见谅!
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