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肝细胞 hepatocytes
0 C" {+ s% \9 f6 l3 B1 Rashid, S.T. et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. The Journal of Clinical Investigation 120, 3127-3136 (2010). 4 _/ w) g$ L i1 _+ o2 h
2 Ghodsizadeh, A. et al. Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells. Stem Cell Reviews and Reports 6, 622-632 (2010).
# g5 A$ V+ r/ ~& ]* L+ c& {: F3 Sullivan, G.J. et al. Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology 51, 329-335 (2010).
C2 g* E, S E: p4 Si-Tayeb, K. et al. Highly efficient generation of human hepatocyte–like cells from induced pluripotent stem cells. Hepatology 51, 297-305 (2010).
" m* l5 a. Y5 n/ {" z& U5 Song, Z. et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res 19, 1233-1242 (2009).) a, u7 o9 F; C; z$ B- J
r' ]0 `+ F$ V神经细胞$ g+ j* M* j/ l' a, H" S
neural crest precusors
3 D8 i3 r/ j6 c; \& w6 Lee, G. et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461, 402-406 (2009). , j0 z; p6 f. \& y% L8 S: P9 m+ p
) I B+ w1 S5 j( {, O7 |neuroepithelial cell
$ z9 o3 d ?, x1 q/ u7 Hu, B.-Y. et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proceedings of the National Academy of Sciences 107, 4335-4340 (2010) 1 P5 H% |! K# l0 y
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motor neurons【包括文献7】
1 R7 K* s# K) _ V8 Dimos, J.T. et al. Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons. Science 321, 1218-1221 (2008).
5 M. Y2 Y, A- M0 R( t9 Ebert, A.D. et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-280 (2009). 9 p u3 z" X& _: Q! B
10 Chambers, S.M. et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotech 27, 275-280 (2009).
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; a/ I2 \; _ B, Cdopaminergic neurons of the midbrain 【包括文献10】5 _2 t& a0 L0 W6 a$ b* g5 m* r
11 Soldner, F. et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell 136, 964-977 (2009). 5 R9 n7 F+ W9 b) I3 I
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glia 【包括文献7,8】
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视网膜细胞+ l3 @7 h. z% j! d* G
Retinal Pigmented Epithelium
: t: G5 X) w! Z( `0 S" M3 p5 p12 Buchholz, D.E. et al. Derivation of Functional Retinal Pigmented Epithelium from Induced Pluripotent Stem Cells. Stem Cells 27, 2427-2434 (2009).& r9 e: @5 a' U% U& w* [) E; B
9 j. s- r$ I5 d) K: k! U7 @; h4 C' aretinal cells8 T4 F" k3 d( Z0 E' O$ c
13 Osakada, F. et al. In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci 122, 3169-3179 (2009).
$ F( @+ r+ }1 s14 Meyer, J.S. et al. Modeling early retinal development with human embryonic and induced pluripotent stem cells. Proceedings of the National Academy of Sciences 106, 16698-16703 (2009).
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' m( A0 W [5 ^! P) ]心肌细胞 cardiomyocytes
) F4 F1 ?2 L9 D* D5 l/ d+ P8 u$ [15 Moretti, A. et al. Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome. New England Journal of Medicine 363, 1397-1409 (2010).4 R6 ], I* s8 ?8 `* ]0 b3 o# ?
16 Carvajal-Vergara, X. et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 465, 808-812 (2010).
" K% S6 k# D) g17 Zhang, J. et al. Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells. Circ Res 104, e30-41 (2009).$ C, y4 c, |' O4 Z: k
18 Zwi, L. et al. Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells. Circulation 120, 1513-1523 (2009).+ W3 W% K: N: D0 z) x2 {
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血管和血液相关细胞
- @ |/ K8 t8 N" H+ Chaematopoietic progenitors5 ^5 r, h9 }4 Y" q7 r
19 Ye, Z. et al. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114, 5473-5480 (2009).
0 H2 H1 l( G) M4 y20 Raya, A. et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460, 53-59 (2009).
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/ @9 I5 W# U3 D, Cblood cells
' H2 B1 @. z9 x4 Z21 Choi, K.-D. et al. Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells. Stem Cells 27, 559-567 (2009).; K9 V4 X+ W8 @" ?* W9 S! k5 s
0 F, ^1 m3 o7 k. n9 Uvascular endothelial cells【包括文献21】5 e$ F/ l9 i% v7 [1 [+ L
22 Feng, Q. et al. Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence. Stem Cells 28, 704-712 (2010).$ x0 Y7 [. v! M: K1 F" A1 s
23 Taura, D. et al. Induction and Isolation of Vascular Cells From Human Induced Pluripotent Stem Cells--Brief Report. Arterioscler Thromb Vasc Biol 29, 1100-1103 (2009).
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$ e/ g6 s* v T* y0 d$ y胰岛素产生细胞 insulin-producing cells
- G$ N2 @, d6 S! E9 a- c24 Maehr, R. et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proceedings of the National Academy of Sciences 106, 15768-15773 (2009).
: Z, J7 n7 A1 f3 D- z25 Zhang, D. et al. Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res 19, 429-438 (2009).
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' z- F6 m% E6 u4 ^! l, j原生殖细胞 primordial germ cells3 @* {2 D! n1 {/ H. I
26 Park, T.S. et al. Derivation of Primordial Germ Cells from Human Embryonic and Induced Pluripotent Stem Cells Is Significantly Improved by Coculture with Human Fetal Gonadal Cells. Stem Cells 27, 783-795 (2009).8 f, ]* Y W( q& N, K' W% |
. N- Z; o9 P& r9 w0 i, ^! q. V% s脂肪细胞 adipocyte; l- _& o1 I- |& D+ u
27 Taura, D. et al. Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells. FEBS Letters 583, 1029-1033 (2009).
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0 N6 [7 J* f [8 L( [( s1 J; F可能会有失误的地方,见谅!
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