2010年12月09日 Nature 主要内容

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（选自英国Nature杂志，2010年12月9日出版）% [# ?/ }( l) I4 p5 {; f$ S

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封面故事：“发育沙漏”的验证. c* r, C" _6 G$ \9 Q5 s
Gene expression divergence recapitulates the developmental hourglass model / A phylogenetically based transcriptome age index mirrors ontogenetic divergence patterns
8 w% w0 ~& l% w1 Ihttp://www.natureasia.com/ch/nat ... 1051&issue=73257 u, m' a, P) W
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拉沙热核蛋白的结构（Lassa fever nucleoprotein structure）
1 l. x: u8 a4 H3 V; TCap binding and immune evasion revealed by Lassa nucleoprotein structure& @+ f; @7 v1 ]
http://www.natureasia.com/ch/nat ... 1044&issue=7325
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RNase P的晶体结构被确定（Ribozyme RNase P dissected）
1 z+ O2 V% h( U" M" CStructure of a bacterial ribonuclease P holoenzyme in complex with tRNA& T. x+ S6 T8 Z% ~! x8 A
http://www.natureasia.com/ch/nat ... 1045&issue=7325; n$ z* K& n2 b7 T

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半胱氨酸残迹内在活性的测定（The cysteines that really count）
: X! a  S8 p0 z8 d% ?& {Quantitative reactivity profiling predicts functional cysteines in proteomes* |7 T4 }8 k  U; U; C% _8 ]5 c
http://www.natureasia.com/ch/nat ... 1046&issue=7325: W, R0 [/ x. a* o
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与宇宙中气体再电离有关的谱线被观测到（A new look at the reionization of the Universe）
, @/ @; B8 Q+ d) XA lower limit of Δz > 0.06 for the duration of the reionization epoch
' {, r' E1 t9 dhttp://www.natureasia.com/ch/nat ... 1047&issue=73254 x5 k- F1 J  R
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0 n4 V3 N# a# ?2 u+ W* @原子运动的实验观测（Atomic motion observed）* S# I( I, ]  V/ c, e
Snapshots of cooperative atomic motions in the optical suppression of charge density waves
* X- p; Q( {1 P! K9 {! w! jhttp://www.natureasia.com/ch/nat ... 1048&issue=7325
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8 m$ `  i# x1 `+ f  ?“波动-响应定律”的确适用于活细胞（Bacterial reaction to small stimuli）
5 V. J: `6 @" W- P, ?Interdependence of behavioural variability and response to small stimuli in bacteria% d  L, b& U. A7 G; F3 T  I0 A% I
http://www.natureasia.com/ch/nat ... 1053&issue=7325
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成胶质细胞瘤揭秘（Tumour cells that supply their own blood）
  d& a6 s8 p1 H9 r8 {9 q$ c: NTumour vascularization via endothelial differentiation of glioblastoma stem-like cells / Glioblastoma stem-like cells give rise to tumour endothelium
7 S2 v4 v# X1 {( s- B' Ihttp://www.natureasia.com/ch/nat ... 1054&issue=7325
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' G% k5 s" v) L6 y) c与磷脂拼接酶活性有关的一种蛋白（Phospholipid scrambling）
9 F( ?4 f3 c! ?% YCalcium-dependent phospholipid scrambling by TMEM16F
1 L& M% A0 c* j: O; Q. x$ K1 Ohttp://www.natureasia.com/ch/nat ... 1056&issue=73255 u0 `! p1 U# T. w- S* U) X/ m1 @8 u
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骨癌中发生突变的TET（Mutated TET in myeloid cancers）
# b# Q$ O  e( U( yImpaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
/ _; `3 d7 w7 ]( E7 [; f; Ehttp://www.natureasia.com/ch/nat ... 1057&issue=7325; j' b4 d0 H0 e" b

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野生型运输因子为什么是同型二聚体？（Why use two when one will do?）
, T3 g& b- v* Q: YDesign, function and structure of a monomeric ClC transporter! W4 ^, E. l  Z
http://www.natureasia.com/ch/nat ... 1058&issue=7325