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两篇俄国科学院物理学杂志上关于生命的review文章,供有兴趣的朋友参考。专注于具体方向研究的生物学家,也需要有更广阔的视野,并对生命本质及其哲学、物理和其他科学探索历史和现状有基本的了解。本站有朋友贴过E-薛定谔的经典文献What's life,这里的两篇2010年文章也有涉及。列出“内容”供参考。' @) c4 c1 `# P) ]8 l+ }9 f
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How in the 20th century physicists, chemists and biologists answered the question: what is life?
' r% T* e; }4 w2 n* T! mV P Reutov, A N Schechter
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Contents
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1. Introduction9 o1 M6 P- b8 q H
2. Main hypotheses concerning the origin of life on Earth
0 s! _& z* W0 x! m& [. d* p3. We have failed to uncover something of major importance
$ f0 k E& I4 Y& i4 g W4. How to close the gap between knowledge and understanding?& \- E4 i! q! H W6 A+ k; {/ p |% y
5. The data that served as the basis for the DNA model
7 o9 N, ]1 Y6 x1 m+ t- I% E* M/ ?/ {6. The profound foresight of James Watson and Francis Crick* ]5 L8 c+ ?/ w
7. Maurice Wilkins and Rosalind Franklin
8 ~; L3 M/ T, \2 ]2 P& V- O8. James Watson and Francis Crick2 f* S! N. E0 Z. H/ y
9. Is the knowledge of the DNA structure sufficient to answer the question `What is life'? 0 @2 R' f4 V! N8 l& h- y
10. N K Koltsov's idea of the matrix replication of biological molecules 6 }6 r$ s) |; q0 x6 m) z$ g S
11. NWTimofeeff-Ressovsky's conclusion: a gene is a tiny compact structure
2 D7 y# Z" i$ f* \12. ``Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid''Ð a paper published in Nature1 ^' k9 |! ?& [1 y6 O/ s
13. G A Gamow's idea of a universal code4 y" l) i7 g" M
14. Nobel Prize in Physiology or Medicine 1962 . E; ?! _: F0 {' h2 h/ P+ q, r( U
15. AMOlovnikov's idea of the role of telomeres in cell mitosis and the Nobel Prize in Physiology or Medicine 2009: {! v9 W5 U' L% ?' U/ {
16. Prospects
0 A, I- i, P( Z17. Conclusions
4 f- h% Z+ ~5 v3 W/ A# `: n18. Appendices/ o" H: R0 | R* u, `/ s
I. Rosalind Franklin: talent and fate;
/ d% d% Q! S8 W5 B; A" Q! f II. James Watson, post-Nobel Prize;
# H. q, b) H( z7 o, o III. Francis Crick, post-Nobel Prize; & u0 e( K& K5 b' @% Q* `5 h; x
IV. James Watson's lectures in Moscow in 2008; 5 I' F& z9 L) p) D1 i, ]. a' ?
V. What conclusions can we draw after analyzing the history of the discovery of DNA and James Watson's lectures?8 @( w- Z! K" M& v, }! i& \) w- c7 H: T
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) K1 d4 O8 t( g* c% L7 r21st century: what is life from the perspective of physics?2 |5 O: l! h0 O' R
G R Ivanitskii
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Contents
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2 d& | T' D* s* j3 M( V) u3 _1. Introduction
7 t. K9 S: k1 u# X2 T6 o- I5 ?2. Life. The problem of definition
b- U" G/ P0 |! ? 2.1 The change in paradigm;
/ N' R: n) @/ P$ U 2.2 The advent of new biophysical sciences (genomics, proteomics, metabolics); 9 D" j8 v& x' i8 V
2.3 The evolutionary history of living organisms at a molecular level;
% N$ Y; Y1 b+ g' [0 } 2.4 Identification of factors accelerating the evolution of living systems; & N3 c8 O9 W6 p2 H. A4 I
2.5 Borderline between living and nonliving matter8 T# y, t0 A) K. Y: V3 j3 c! l3 \8 U
3. Interplay between living and nonliving matter (ten paradoxes)
& {2 N2 a* |8 t' d) C9 R 3.1 Plato±Socrates' paradox;
4 x- R; e0 f* E0 q! a 3.2 Zeno's paradox;
6 v7 O2 q! F, H8 K( ^% K 3.3 Maxwell's demon paradox;
$ t. A% _9 @ b1 @4 } 3.4 Schrodinger's cat paradox;& r1 V! B6 v, C/ w& N
3.5 Stochastic ratchet paradox; $ q0 k' x/ B# k! n( z- E) U5 K
3.6 Paradox of time deficit; q# Q9 Z) a4 h8 G0 q0 e+ `
3.7 Paradox of homochiral structure;
7 n5 }; R& f! ^- H4 N2 s 3.8 Paradox of the part and the whole; 3 g) G" z2 f6 A Q- A% L3 W( P
3.9 Saint Petersburg paradox;
( t$ m: a- G2 r5 w& T3 a2 ]; k2 P$ ] 3.10 Buridan's ass paradox
# `% @. _# h- i0 i0 }3 B" D4. Discussion
, M/ N+ b0 p* M2 R; s' Z3 Q4 X5. Conclusion
1 e: s3 _$ j: x( g0 }; a( B3 JReferences
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