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本帖最后由 细胞海洋 于 2012-2-12 20:36 编辑 $ C! ?2 {" Z* R2 Z
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研究显示有接触性过敏反应的人可能不易患癌
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来源：新华网 发布时间：2011-7-21 13:42:05选择字号：小 中 大 + e" n1 |' M8 j
' I, D. d# L( ~6 {美国趣味科学网站7月18日报道，过敏的人可能不易患癌。
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$ D7 M$ j0 V3 o, p过敏很烦人，但一项新的研究表明，过敏其实可能有好处，存在接触性过敏反应的人其免疫系统或许能防范某些类型的癌症，其中包括乳腺癌和非黑色素瘤皮肤癌。
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% m# A: b+ M1 I; i& A6 j科学家对将近1.7万名存在接触性过敏反应的丹麦成年人展开了研究。这些人会因为直接接触丙酮等化学品以及镍和钴等普通金属而发生过敏，接触过敏原的地方会在24小时之内出现皮疹。
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& J! L+ J! d2 ?1 x" b% Y大约1/3的研究对象至少对一种接触性过敏原呈阳性反应，女性呈阳性反应的比例(41%)高于男性(26%)。他们接受检查的时间是1984年到2008年。' F2 j* _, S0 @ i: ^4 |4 y) i
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哈佛大学2011年4月的一项研究报告指出，在美国，受接触性过敏困扰的人口有3000万-4500万，超过美国总人口的10%。
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/ N5 Z7 o7 K6 Q6 s1 w! \哥本哈根大学根措夫特医院全国过敏研究中心的研究人员长期跟踪研究对象罹患癌症的情况。结果表明，与其他人群相比，存在接触性过敏反应的人罹患乳腺癌和非黑色素瘤皮肤癌的比例要低得多。- t1 b1 } f, _ M% _5 `6 G; O
% K# u2 g2 ?4 t6 i; V' z" _研究还表明，与没有接触性过敏反应的女性相比，存在接触性过敏反应的女性罹患乳腺癌的比例较低，但在统计数据方面并不显著。不过，研究人员发现，存在接触性过敏的男性和女性患膀胱癌的比例较高，这“可能是因为化学代谢物堆积在膀胱中造成的”。& l" r7 g) O% ?/ B! B
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存在接触性过敏的人罹患脑癌、乳腺癌和非黑色素瘤皮肤癌的比例之所以较低，可能与他们的免疫系统的运作方式有关。研究人员说，研究结果证实了免疫监视假说。根据该理论，具有高免疫力的人会受到过敏的困扰。这种高免疫力或许能防范某些癌症。$ v0 T3 D- p! S- Z& S* `! G/ q
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研究人员告诫说，研究结果表明接触性过敏与某些癌症低发之间存在关联，但并不表明两者之间有必然的因果关系。
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5 Q+ o- _0 S- ~2 n0 x7 B The Good News on Allergies: They Might Protect Against Cancer
* F' I6 z) W3 SRemy Melina, LiveScience Staff WriterDate: 18 July 2011
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Allergies are a pain, but a new study suggests that they may actually be helpful. The immune systems of people with contact allergies may be primed to protect against some forms of cancer, including breast and non-melanoma skin cancer, according to a new study.8 Y0 C" u/ ~) Q
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Scientists focused on nearly 17,000 Danish adults who were tested for contact allergies, when an allergic reaction occurs due to direct contact with chemicals such as acetone and common metals, including nickel and cobalt. People with contact allergies usually develop a rash on the area that touched the allergen within 24 hours.& b; Z9 k9 R- j; m. g/ V: C6 g5 v
0 V( j8 \) ^* |# QAbout one-third of the study participants tested positive for at least one contact allergy, with women more likely to test positive (41 percent) than men (26 percent). The participants were tested between 1984 and 2008.
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% a$ m) u5 u; \; ^) u5 jScientists estimate about 20 percent of the general Danish population has contact allergies; In the United States, 30 million to 45 million people have contact allergies —or more than 10 percent of the U.S. population, according to an April 2011 Harvard study.3 C0 x( O% E/ O# Z. `3 m4 ~& e% l
% i0 Z1 g( q0 L; D) pResearchers at the National Allergy Research Centre at Copenhagen University Hospital Gentofte in Hellerup, Denmark, examined cancer cases among the study participants over the long term. The findings showed that men and women with contact allergies had significantly lower rates of breast cancer and non-melanoma skin cancer./ V, Z9 \# g |5 S; j' c
; V9 U, P4 Z9 I9 C4 @3 I$ Y( lThe study also showed that women with contact allergies had lower rates of brain cancer compared with women without contact allergies, though that was not statistically significant. However, researchers found that both men and women with contact allergies had higher rates of bladder cancer, which "could be due to accumulations of chemical metabolites in the bladder," according to the study.
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0 x/ i; O7 a b, p4 ZThe lower rates of brain, breast and non-melanoma skin cancer among those with contact allergies may be the result of how their immune systems function. According to researchers, the findings support the immunosurveillance hypothesis — the theory that individuals with so-called hyperimmunity have the side effect of allergies. This hyperimmunity is what may protect against some cancers.
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The researchers caution that the results show a correlation between contact allergies and lowered rates of some cancers, but do not mean that one caused the other.2 g; `) o) [% x* Y5 n' o
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发表于 2011-7-21 21:33
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