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Non-Viral Gene Therapy% j8 M! k) q7 Z1 z; n
Edited by: Xu-bo Yuan' H$ H3 R. }: O9 R4 }' J, Z
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ISBN 978-953-307-538-9, Hard cover, 696 pages
& {1 H4 u: j" @( CPublisher: InTech
' f0 B6 i5 c6 d5 s! D) H& aPublication date: November 2011" [# @! p, E1 Q
Subject: Gene Therapy1 y- K7 }; Z3 ?. H4 p
2 O+ }) ?: X" @This book focuses on recent advancement of gene delivery systems research. With the multidisciplinary contribution in gene delivery, the book covers several aspects in the gene therapy development: various gene delivery systems, methods to enhance delivery, materials with modification and multifunction for the tumor or tissue targeting. This book will help molecular biologists gain a basic knowledge of gene delivery vehicles, while drug delivery scientist will better understand DNA, molecular biology, and DNA manipulation.
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3 A0 L+ D7 h$ t1 h9 B7 UTable of Contents
0 s) x. ~* R- m& uNon-Viral Gene Therapy Vectors Carrying Genomic Constructs
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Non-Viral Delivery Systems in Gene Therapy and Vaccine Development
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8 Z- t* @- d7 i2 @Gene Delivery Systems: Tailoring Vectors to Reach Specific Tissues
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Investigation of Transfection Barriers Involved in Non-Viral Nanoparticulate Gene Delivery in Different Cell Lines+ ^1 }# V6 V/ M: C3 n3 P* G! x$ p
9 R4 j- W |8 _1 m, \7 x* mThe Mechanical Agitation Method of Gene Transfer for Ex-Vivo Gene Therapy# E: H; |+ t* d+ K" v
( ?1 J7 C* T' ]& Q1 ?Gene Therapy of Some Genetic Diseases by Transferring Normal Human Genomic DNA into Somatic Cells and Stem Cells from Patients
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Non Viral Gene Transfer Approaches for Lysosomal Storage Disorders) h% C' q% E& Z- y# m$ ?
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DNA Vaccination by Electrogene Transfer
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Gene Delivery with Ultrasound and Microbubbles
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Ultrasound-Mediated Gene Delivery
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Polyamine – Lipid Conjugates as Effective Gene Carriers: Chemical Structure, Morphology, and Gene Transfer Activity( X, i7 X& y! T2 G9 c
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Technological Aspects of Scalable Processes for the Production of Functional Liposomes for Gene Therapy |% i2 [) Z+ b; r/ ]
`- f: O) Y% H# hCationic Liposomes in Different Structural Levels for Gene Delivery
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5 ^3 V, {, g5 M4 Q# N; DNeutral Liposomes and DNA Transfection
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Non-Viral Gene Delivery Systems Based on Cholesterol Cationic Lipids: Structure-Activity Relationships
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2 H. l* @; D' D1 h/ cPolycation-Mediated Gene Delivery: The Physicochemical Aspects Governing the Process
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' C; r- J1 v& {% h* bMedical Polymer-Based Gene Therapy0 M# s+ l. S' K! d& J
( l4 { z5 k X1 A9 Z) G9 d5 DChitosan and Its Modifications: Are They Possible Vehicles for Gene Therapy?5 F6 x! ~) `3 D
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Chitosan-DNA/siRNA Nanoparticles for Gene Therapy
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) `" i$ @. Y) S' l( w: o5 _Toxicity of Polymeric-Based Non-Viral Vector Systems for Pulmonary siRNA Application5 ^) H' [/ r3 O" I* X5 t" h% T
1 ^% X. _( @4 j. C, fPAMAM Dendrimer as Potential Delivery System for Combined Chemotherapeutic and MicroRNA-21 Gene Therapy
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Nanomedicine Based Approaches to Cancer Diagonsis and Therapy
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Toxicogenomics of Nonviral Cationic Gene Delivery Nanosystems1 F7 Q( b& T) l4 G n
! R5 |4 q8 O4 Q% rNano-Particulate Calcium Phosphate as a Gene Delivery System$ ~# F; y1 Y4 }$ [
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Modular Multifunctional Protein Vectors for Gene Therapy% @. U; E3 D# H: |0 }1 `+ B9 N+ X
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Peptides as Promising Non-Viral Vectors for Gene Therapy
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Binding of Protein-Functionalized Entities onto Synthetic Vesicles9 E% k* f0 t* |2 e
2 n9 e. w* Y1 j, q. RTargeting TRAIL Receptors with Genetically- Engineered CD34+ Hematopoietic Stem Cells
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Pyrrole-Imidazole Polyamides for Gene Therapy: Bioanalytical Methods and Pharmacokinetics
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