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Non-Viral Gene Therapy
. ^. m/ ?. \1 M+ O5 n" F; wEdited by: Xu-bo Yuan8 ]3 t8 k$ j- z G6 u1 f: C& z/ A
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J0 Z8 }6 Z; I5 ]ISBN 978-953-307-538-9, Hard cover, 696 pages1 U/ ]7 D& U N2 {' U4 O0 b7 v7 k
Publisher: InTech' V) L: t. U s- ^/ |5 d5 O6 m @: L
Publication date: November 2011( n! T9 M" t, ]7 b$ M0 j/ {% b
Subject: Gene Therapy
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This book focuses on recent advancement of gene delivery systems research. With the multidisciplinary contribution in gene delivery, the book covers several aspects in the gene therapy development: various gene delivery systems, methods to enhance delivery, materials with modification and multifunction for the tumor or tissue targeting. This book will help molecular biologists gain a basic knowledge of gene delivery vehicles, while drug delivery scientist will better understand DNA, molecular biology, and DNA manipulation.( e2 }: D6 V6 r! `
2 U k9 {+ `% d1 B" WTable of Contents$ d; D A$ P4 s
Non-Viral Gene Therapy Vectors Carrying Genomic Constructs
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3 ^* \% h" W; g% oNon-Viral Delivery Systems in Gene Therapy and Vaccine Development
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3 ?% o! p% d zGene Delivery Systems: Tailoring Vectors to Reach Specific Tissues$ \/ w( i+ _* C2 [3 R0 }2 Y
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Investigation of Transfection Barriers Involved in Non-Viral Nanoparticulate Gene Delivery in Different Cell Lines
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The Mechanical Agitation Method of Gene Transfer for Ex-Vivo Gene Therapy
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% S- J$ n: N6 EGene Therapy of Some Genetic Diseases by Transferring Normal Human Genomic DNA into Somatic Cells and Stem Cells from Patients9 j# v4 h2 o' J: N8 i0 g: a
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Non Viral Gene Transfer Approaches for Lysosomal Storage Disorders5 C" ?2 J/ r$ V. W
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DNA Vaccination by Electrogene Transfer& d2 P. g3 v7 Y' k: F
" Z, w- B9 n2 |Gene Delivery with Ultrasound and Microbubbles
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Ultrasound-Mediated Gene Delivery
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- y4 Z/ D0 `; D/ m. D" G7 |" kPolyamine – Lipid Conjugates as Effective Gene Carriers: Chemical Structure, Morphology, and Gene Transfer Activity& l& g5 U* Z+ B/ H( }% ?
4 x$ B" y! G2 m2 b4 Q7 GTechnological Aspects of Scalable Processes for the Production of Functional Liposomes for Gene Therapy: j9 F, a ~. B) q* [1 l
; @; o8 {$ g) {Cationic Liposomes in Different Structural Levels for Gene Delivery
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; Q: {4 e- E( {& p ^8 DNeutral Liposomes and DNA Transfection
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Non-Viral Gene Delivery Systems Based on Cholesterol Cationic Lipids: Structure-Activity Relationships
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Polycation-Mediated Gene Delivery: The Physicochemical Aspects Governing the Process0 S1 f7 l( k, c0 D/ k
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Medical Polymer-Based Gene Therapy( g' i: e' g# z) B* {* ]
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Chitosan and Its Modifications: Are They Possible Vehicles for Gene Therapy?& ~! L! C' u+ G
& G6 u" { `: R: A5 M! B1 P( Z+ \Chitosan-DNA/siRNA Nanoparticles for Gene Therapy
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5 F* h2 @3 F1 ZToxicity of Polymeric-Based Non-Viral Vector Systems for Pulmonary siRNA Application+ B5 ~" x+ f$ _: \" `7 ^' t
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PAMAM Dendrimer as Potential Delivery System for Combined Chemotherapeutic and MicroRNA-21 Gene Therapy
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" A3 I d& K' e) x( j# T7 tNanomedicine Based Approaches to Cancer Diagonsis and Therapy
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8 B0 T0 f+ F+ CToxicogenomics of Nonviral Cationic Gene Delivery Nanosystems2 F5 R9 G: V7 {
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Nano-Particulate Calcium Phosphate as a Gene Delivery System
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Modular Multifunctional Protein Vectors for Gene Therapy
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Peptides as Promising Non-Viral Vectors for Gene Therapy) `' }, B8 u' O6 B. B
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Binding of Protein-Functionalized Entities onto Synthetic Vesicles; t: F" w! X" I0 _6 s9 p/ X
/ U0 _8 o: l! F7 Y. k! `2 U2 ITargeting TRAIL Receptors with Genetically- Engineered CD34+ Hematopoietic Stem Cells
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Pyrrole-Imidazole Polyamides for Gene Therapy: Bioanalytical Methods and Pharmacokinetics
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