- 积分
- 6084
- 威望
- 6084
- 包包
- 18316
|
Non-Viral Gene Therapy
- T& a- ~3 s0 IEdited by: Xu-bo Yuan* f9 g. z, g/ q2 Z$ l% O @" c9 s
6 E) _( {" ~& B1 K- u6 x3 ]* W8 Z7 M2 q; {+ i
ISBN 978-953-307-538-9, Hard cover, 696 pages( B6 T% X, J' q# F) q
Publisher: InTech g" s( c$ n* k5 n/ W7 Z! s
Publication date: November 2011
: e, {6 q2 ^4 N1 h' ?" B, ySubject: Gene Therapy
. a) m: _8 N: Y5 z) u3 @! {" Y6 x1 f" q/ G) G% Q/ h; o
This book focuses on recent advancement of gene delivery systems research. With the multidisciplinary contribution in gene delivery, the book covers several aspects in the gene therapy development: various gene delivery systems, methods to enhance delivery, materials with modification and multifunction for the tumor or tissue targeting. This book will help molecular biologists gain a basic knowledge of gene delivery vehicles, while drug delivery scientist will better understand DNA, molecular biology, and DNA manipulation.: y5 V2 B; n H1 Q* o: m
$ P% s5 p. s, }9 ^6 f
Table of Contents9 N9 C/ \) \$ k+ G8 a
Non-Viral Gene Therapy Vectors Carrying Genomic Constructs! x' d1 |2 u5 Q0 e) ?2 I5 u
2 u6 x# k) _4 {7 c7 ?4 BNon-Viral Delivery Systems in Gene Therapy and Vaccine Development
6 S4 P" t% N) h1 E& F7 U5 I1 ~# I4 U8 J5 [& x. w
Gene Delivery Systems: Tailoring Vectors to Reach Specific Tissues5 \& a. z9 G( V0 w3 J0 B
( G+ H. W9 P6 H2 @" y0 |Investigation of Transfection Barriers Involved in Non-Viral Nanoparticulate Gene Delivery in Different Cell Lines8 Q" d8 C- ~; q8 I/ e
0 O* v% V" u- x# W, mThe Mechanical Agitation Method of Gene Transfer for Ex-Vivo Gene Therapy
; [8 s' Y2 V6 @7 |. v, Q& Y8 x% g2 J0 W0 P3 g; d7 C# g* _( p
Gene Therapy of Some Genetic Diseases by Transferring Normal Human Genomic DNA into Somatic Cells and Stem Cells from Patients [6 s% `2 {& k W5 e/ ], Q! q
' o; ~0 v2 u, U0 [
Non Viral Gene Transfer Approaches for Lysosomal Storage Disorders$ r. N; {' q- r) L
5 |9 D5 C. R$ @3 rDNA Vaccination by Electrogene Transfer
% t* u4 f7 s7 [( s) |6 I c% u! G( }2 H7 z a
Gene Delivery with Ultrasound and Microbubbles. \/ Y9 y4 x$ c( o3 o% G
7 }- v# g+ i4 X! P* e" x
Ultrasound-Mediated Gene Delivery
8 e) U4 ~$ u) C0 ~ P3 M
! ^9 C& q# v9 Y4 M" X; GPolyamine – Lipid Conjugates as Effective Gene Carriers: Chemical Structure, Morphology, and Gene Transfer Activity
# ?, O' T& u! ]: X, r5 j
5 h! H4 v7 S0 ~" T6 k3 K" ZTechnological Aspects of Scalable Processes for the Production of Functional Liposomes for Gene Therapy
2 M9 t% H6 X) E& {* |* L( Q; w
4 c1 z/ x$ \2 Z# [! YCationic Liposomes in Different Structural Levels for Gene Delivery4 ?, K: p2 [' ~
* p* u7 ^& T9 `! T1 XNeutral Liposomes and DNA Transfection- H2 U+ C# M2 ~; z* A8 Y; x
( F) t) e3 M# v, f* e
Non-Viral Gene Delivery Systems Based on Cholesterol Cationic Lipids: Structure-Activity Relationships
5 {; ~( \! {( e/ n/ S8 \
% v6 k" I' N, x+ E5 y3 z$ }Polycation-Mediated Gene Delivery: The Physicochemical Aspects Governing the Process
4 R- d- r) w# P$ t: m! N$ R% F
0 d' I; W+ e* q7 X6 `Medical Polymer-Based Gene Therapy' H& D& u- r7 w3 M9 y
. U6 \3 C5 Q% s; N* ]Chitosan and Its Modifications: Are They Possible Vehicles for Gene Therapy?% v7 U" X7 \+ E; N8 W
( Z2 N: M8 d* w2 R2 x/ l. l
Chitosan-DNA/siRNA Nanoparticles for Gene Therapy
' I/ \/ L' e8 B/ I
# a. A. o8 ~+ ^1 H, WToxicity of Polymeric-Based Non-Viral Vector Systems for Pulmonary siRNA Application) y4 K9 _7 d8 D3 t8 y8 [
2 @/ V) b8 n& a6 D- `PAMAM Dendrimer as Potential Delivery System for Combined Chemotherapeutic and MicroRNA-21 Gene Therapy8 Y2 k# B4 q& {
: U! {# J Q7 `, s; X
Nanomedicine Based Approaches to Cancer Diagonsis and Therapy
: f" Z9 N; u8 {1 j* v+ K1 Z
- C$ K- H6 W+ L6 @1 ]1 uToxicogenomics of Nonviral Cationic Gene Delivery Nanosystems
) E \7 D1 T6 [, y4 }; |2 d# o$ ?6 r1 W1 a
Nano-Particulate Calcium Phosphate as a Gene Delivery System- d4 K' ?) X' O
! b+ X4 t7 N- {' G3 D& \5 Q
Modular Multifunctional Protein Vectors for Gene Therapy
- k9 L0 ?! N% _8 s1 h9 r: o! R# _$ d
/ n2 ]7 e+ G+ DPeptides as Promising Non-Viral Vectors for Gene Therapy
$ P' ?" }7 x: Q5 Y
1 B% Y- Y- X3 i" M: J3 O4 @( HBinding of Protein-Functionalized Entities onto Synthetic Vesicles
8 T S. F2 w# v9 K+ ~
) E* C$ m, v" G! UTargeting TRAIL Receptors with Genetically- Engineered CD34+ Hematopoietic Stem Cells; d' F% T7 M/ Y
4 Q# O% Z8 _; ~ R! nPyrrole-Imidazole Polyamides for Gene Therapy: Bioanalytical Methods and Pharmacokinetics7 Z9 k1 }: c- ^2 S0 k, y& n) @
: a9 z2 @' |: e6 h- k( W( `9 h6 o! }2 S |
附件: 你需要登录才可以下载或查看附件。没有帐号?注册
-
总评分: 威望 + 20
包包 + 20
查看全部评分
|