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从权威杂志 blood, cancer research, cancer cell, cell ,cell stem cell, cell research, stem cells, PNAS, nature 系列等收集了74篇研究性论文,与大家分享。
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& N0 G: H; _# Z$ p2 eJiang, X. 2010 Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate.
+ e$ R- j* Z- l$ ?- U5 aBlood
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Peng, C. 2010 PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice.4 s: s: a" q6 |' G+ ^7 a
Blood
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! }" t/ E* |' j9 USengupta, A. 2010 Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo.; k. s, S6 S1 `( q
Blood
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Smith, A. C. 2010 High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.
4 f. n4 x8 f0 O/ TBlood
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8 X; Q: U, u. _9 A. [Taussig, D. C. 2010 Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.- {3 V5 ^) R0 d( A3 e! J
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Chen, R. 2010 A hierarchy of self-renewing tumor-initiating cell types in glioblastoma.
' t9 P0 H5 |7 J) x. q% G* f9 @Cancer Cell
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Yeung, J. 2010 β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells.
$ }* _$ a: }. [( rCancer Cell9 |7 j# O$ C* m% ^2 P0 o# @
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, [) i3 ?# I7 S. LZhang, B. 2010 Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.
$ a9 S) b0 `& e7 S9 L r) k _$ aCancer Cell
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Biernacki, M. A. 2010 Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells.
" ?, l$ {, _+ A- n5 W( b. U7 oCancer Res
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Bonnefoix, T. 2010 Cancer stem cells promote tumor vascular development--letter.
! Y# j8 G) e% ~4 UCancer Res
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Cammareri, P. 2010 Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells.1 D3 A7 O6 b2 n k4 B
Cancer Res
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. t1 F; S7 B/ bChiou, S. H. 2010 Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.5 k- u. E+ a$ M4 V" ^* [. a. ]' y
Cancer Res- M$ A% E* T4 j: y: V5 V
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6 b5 U% O, C5 L4 H5 tDeka, J. 2010 Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.) M; x! ^$ [4 j, g
Cancer Res
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Harrison, H. 2010 Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor./ c0 c& h& f' _( Q0 s2 h5 H
Cancer Res
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$ r" M* T( S: _9 gHebbard, L. W. 2010 Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo.
, K2 l/ o* i7 _. XCancer Res0 B/ ^( V" E5 i- I9 c/ u
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+ f: y6 y3 A" o% E8 [/ ^Held, M. A. 2010 Characterization of melanoma cells capable of propagating tumors from a single cell.
+ C: | W& K; H9 DCancer Res
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Jin, Y. 2010 Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species.) G* a; R/ W# G* g& F- l. `! t, s
Cancer Res8 i }0 W6 S* R: n
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8 Y& i: x; {5 m' C0 s1 dJo, M. 2010 Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells.
3 w" Y' i6 |5 m7 N! \Cancer Res, |1 n- m7 [, M' R
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Joseph, I. 2010 The telomerase inhibitor imetelstat depletes cancer stem cells in breast and pancreatic cancer cell lines.- p1 I: J- Q8 [7 Q' \
Cancer Res
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7 M3 n* G9 v0 e0 z9 t' H8 O# SKemper, K. 2010 The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation.
% v! \9 c: I* D- _2 E6 rCancer Res
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! y3 Y" F8 s3 l4 b# ?1 c( XKrishnamurthy, S. 2010 Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells.6 V2 Y: Z' E. V* i
Cancer Res
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8 b! b8 _- ^( r3 g ?3 f+ h, gLee, J. H. 2010 Pathways of proliferation and antiapoptosis driven in breast cancer stem cells by stem cell protein piwil2.
E& N; o: q. q4 n/ K5 r: eCancer Res
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- |: r# F6 L, }$ }: kLevina, V. 2010 Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop.
6 G; X% l" k5 G8 BCancer Res: O1 }3 j9 f! ]! |, W3 ]
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Liao, C. P. 2010 Cancer-associated fibroblasts enhance the gland-forming capability of prostate cancer stem cells.
+ s0 ^0 N" Y- L. |2 N; \9 K5 tCancer Res
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Liu, M. 2010 The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.
' E5 p4 }; c. t9 qCancer Res/ M$ f1 Y( u) j4 z
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Lottaz, C. 2010 Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin.
5 P% l: }: \7 r4 ]2 k g4 H3 [Cancer Res5 Y4 g! B, m3 @/ J( B2 W3 o
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" L! i0 l& |7 h; f( VMazzoleni, S. 2010 Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis. r: I3 E p' _, l; }" u5 m
Cancer Res) E% S x+ o7 X2 x4 m) p9 p( Z+ t
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2 y- l; z4 a0 S" t9 Q' g5 {$ x) u4 bOoi, A. T. 2010 Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer.
* @9 ^9 w& R8 `" u9 dCancer Res
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Reiman, J. M. 2010 Immune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cells.4 f% Q+ [* |; T; q
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- m2 B" S+ Q- x3 A ~1 J6 XSchatton, T. 2010 Modulation of T-cell activation by malignant melanoma initiating cells.! B7 }6 N2 R$ A4 o! Y5 o
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Sikandar, S. S. 2010 NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer.
. T6 u( M$ V5 {6 HCancer Res- l6 h% \& C; J$ R: x2 O
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Sottoriva, A. 2010 Cancer stem cell tumor model reveals invasive morphology and increased phenotypical heterogeneity.
3 H _3 |* g) f% y4 n3 J- b1 rCancer Res
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" V* a j; m" R) r+ V2 |' k" ~Sullivan, J. P. 2010 Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.
8 Q: X; k2 ~5 s9 M6 y# PCancer Res: u2 l9 G7 b# r5 R" m6 I T; z ~, |
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Todaro, M. 2010 Tumorigenic and metastatic activity of human thyroid cancer stem cells.
! [+ l5 \; v. bCancer Res
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- E- V* ^7 ?2 _9 v+ z2 GWong, P. 2010 The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression., ^1 ~1 |3 ~1 c" e: H
Cancer Res5 v1 Y/ w3 j; Y$ Y4 s/ V/ @6 |
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% Y( s0 i& G+ W; D( V' x8 aYang, X. 2010 Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells., ?: s) n8 m; `. r9 n! G
Cancer Res, Y! p2 b2 y5 H, k
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|) Z4 K s0 b+ SPece, S. 2010 Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content.
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Roesch, A. 2010 A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth.: i6 @% J) E1 r' q( T0 j
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: M, ]+ `0 l& m3 x( [0 R2 a! U; OCharles, N. 2010 Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells.; A8 l' J2 n, }) z0 _
Cell Stem Cell
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Kikushige, Y. 2010 TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells.$ b4 e( q! J4 ]5 I
Cell Stem Cell \0 m G' ~, ~4 t6 x9 V4 c$ X
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4 ?! n0 M( I, l* t9 |( c" _& Z! RLathia, J. D. 2010 Integrin alpha 6 regulates glioblastoma stem cells.
1 U7 N. K& J3 @; v1 U7 T4 aCell Stem Cell
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Ma, S. 2010 miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1.# @8 Q7 O6 b1 Z5 L/ W% M6 c. J& t6 I
Cell Stem Cell
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Pang, R. 2010 A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer., I+ z7 b' o; n' Z
Cell Stem Cell
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Wurdak, H. 2010 An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.& w) Z1 X6 h0 Z1 u% N" ?2 C+ D
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% S- a' T7 y) n& n8 a9 w* ?Yang, X. R. 2010 High expression levels of putative hepatic stem/progenitor cell biomarkers related to tumour angiogenesis and poor prognosis of hepatocellular carcinoma.' h4 a3 @1 Q3 @5 W1 E; w' I1 q
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You, H. 2010 Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta.$ g1 U) Q0 \" h V; v1 ^. ]
Hepatology
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2 c. r# b! g7 f" G6 C' d& iCalcagno, A. M. 2010 Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics.* v0 {5 n+ W& u+ e; v
J Natl Cancer Inst7 _0 \6 _; S$ [- Q7 L3 a
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( N( x8 R, Z) _ c: OTehranchi, R. 2010 Persistent malignant stem cells in del(5q) myelodysplasia in remission.
6 u' P% H' ?( E8 x! T+ o3 TN Engl J Med
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* b0 z w- t. m$ Q1 d/ }Saito, Y. 2010 Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.
9 p" J' c! F' ]+ |$ B( t, {$ nNat Biotechnol
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Vermeulen, L. 2010 Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.; ?6 G0 b$ ~- a( t6 Q% s, e' @: u: x `, T
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Youssef, K. K. 2010 Identification of the cell lineage at the origin of basal cell carcinoma.$ X! O5 B s7 F$ W: r3 {8 n; ]
Nat Cell Biol5 \. K: S( e/ L# N6 o9 ]; ]
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Clément, V. 2010 Marker-independent identification of glioma-initiating cells.. [+ ~$ K' J: a1 W- `; e
Nat Methods
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Boiko, A. D. 2010 Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271.5 [9 N" t z# R8 f( o5 N
Nature( B2 y; s9 [8 T+ c: t' J# c7 C
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Naka, K. 2010 TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.
# o1 n9 { e) L& ^$ KNature
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Fillmore, C. M. 2010 Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.
5 O( H; R1 G2 n) u/ DProc Natl Acad Sci U S A
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J爀猀, M. 2010 Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.
! Y- {- V' Y% M4 V4 [( b3 aProc Natl Acad Sci U S A
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Liu, H. 2010 Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models.2 X0 p0 D" B, u: j( K. a
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% C4 _; c- n- z4 a, r$ v- ZMiyoshi, N. 2010 Defined factors induce reprogramming of gastrointestinal cancer cells.3 G0 G m) s0 X" n }( o; u* I: [
Proc Natl Acad Sci U S A
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Mizuno, H. 2010 Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures.
; Y [4 Q0 ?/ B9 @1 ? Y% q, j3 oProc Natl Acad Sci U S A
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Qiu, W. 2010 Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.
; z6 R' H3 l, D# N; T9 f @, L) u# TProc Natl Acad Sci U S A8 A4 K6 p; [( x7 P2 }: _
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& p4 Q8 k" J9 BRouet, V. 2010 Local prolactin is a target to prevent expansion of basal/stem cells in prostate tumors.
& \! K; ?0 o J) F! O! \+ WProc Natl Acad Sci U S A: f: e, X3 O; W" w s4 D( ]9 b# G
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Yeung, T. M. 2010 Cancer stem cells from colorectal cancer-derived cell lines.. z9 J6 w' k. a) W: o
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) E1 e1 N( T. mZhang, M. 2010 Selective targeting of radiation-resistant tumor-initiating cells.2 U: u- V, P7 \% v4 Z% \
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% t. `% k7 T0 l+ p* c: JWang, Y. 2010 The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
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Abou-Kheir, W. G. 2010 Characterizing the contribution of stem/progenitor cells to tumorigenesis in the Pten-/-TP53-/- prostate cancer model.' p4 E$ I q- S/ W' C
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# [. D0 g/ [% w4 R) L/ n7 uStem Cells
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Hovinga, K. E. 2010 Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate.% S. @ Q% `* H9 Y
Stem Cells
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Hurt, E. M. 2010 Identification of vitronectin as an extrinsic inducer of cancer stem cell differentiation and tumor formation.
2 Y7 _. @5 }8 [; JStem Cells' V; A+ @' f! C. V' }" ~
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Naka, N. 2010 Synovial sarcoma is a stem cell malignancy.
8 ]8 h7 @# ?8 [& GStem Cells1 ^2 M0 P/ g0 s
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Sajithlal, G. B. 2010 Permanently blocked stem cells derived from breast cancer cell lines.
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Stuelten, C. H. 2010 Complex display of putative tumor stem cell markers in the NCI60 tumor cell line panel.) p9 q7 b+ r0 Z* D) x! H
Stem Cells
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- d0 d# A+ Z# F5 ?* J- |/ T! ~Sunayama, J. 2010 Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.7 I1 M K' C! Q' b- ~' O
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Wang, J. 2010 Notch promotes radioresistance of glioma stem cells.; b+ p$ O. P0 s
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$ D; [# W# _+ f5 b8 ZWatanabe, K. 2010 Cripto-1 is a cell surface marker for a tumorigenic, undifferentiated subpopulation in human embryonal carcinoma cells.
6 O) g3 b4 `9 jStem Cells* w" s, ~% @8 G! P. \8 X
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