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2012年11月 Nature Medicine
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# j! W6 |. l* i2 A8 R/ [# Q0 MIn this issue, Andrew Weng and his colleagues uncover a new - W; b) `0 q3 A/ J, ^
mechanism by which oncogenes regulate leukemia stem cells. Notch-driven
3 ~* x; l3 t6 iinactivation of PKCθ attenuates the accumulation of ) m7 `& F' u! Z+ F1 s3 ?
reactive oxygen species to lower oxidative stress in the stem cell population of
^& S) T7 o3 ~2 j4 |9 @T cell acute lymphoblastic leukemia (ALL), contributing to tumorigenesis. The , n1 {4 I- r/ A% F S+ _' ]
image shows an electron micrograph of erythrocytes and lymphocytes from a
9 y6 M( e$ b, Rpatient with ALL. Photo by Steve Gschmeissner/Science Photo Library. ) M O$ y7 \0 U/ C
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9 r8 a) A$ U P9 ]. p[hide][/hide] |
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发表于 2012-11-10 12:55
发表于 2012-11-12 16:35
