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2012年11月 Nature Medicine$ ~+ y( _# K5 ]0 S7 d: y
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In this issue, Andrew Weng and his colleagues uncover a new
7 j8 T7 G9 S" W1 T, Imechanism by which oncogenes regulate leukemia stem cells. Notch-driven
& F; s4 E/ L" z6 V& Ninactivation of PKCθ attenuates the accumulation of $ J0 L4 F& ^4 g& y. Z4 O- [
reactive oxygen species to lower oxidative stress in the stem cell population of
0 m" `9 t% g J$ j% W6 iT cell acute lymphoblastic leukemia (ALL), contributing to tumorigenesis. The / Q; s! U! ~ o* I
image shows an electron micrograph of erythrocytes and lymphocytes from a
V: k/ m$ a, T) fpatient with ALL. Photo by Steve Gschmeissner/Science Photo Library.
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- r% S- F& P5 u2 p$ d: P8 k. E[hide][/hide] |
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发表于 2012-11-10 12:55
发表于 2012-11-12 16:35
