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2012年11月 Nature Medicine
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% M* y, M4 f, b' i9 W$ E& `5 Y' e/ xIn this issue, Andrew Weng and his colleagues uncover a new
+ G* K9 t/ I4 |, Tmechanism by which oncogenes regulate leukemia stem cells. Notch-driven
, M9 }. S" W9 N5 qinactivation of PKCθ attenuates the accumulation of $ N- o0 \7 _% o" ?3 O, _ G
reactive oxygen species to lower oxidative stress in the stem cell population of / D9 B0 y( S2 j7 y, ~% @) r
T cell acute lymphoblastic leukemia (ALL), contributing to tumorigenesis. The 9 M5 {3 B8 R& ^- x; S* R9 n3 X
image shows an electron micrograph of erythrocytes and lymphocytes from a
4 x7 L( M% D( i- s* ~* Xpatient with ALL. Photo by Steve Gschmeissner/Science Photo Library.
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8 G/ \4 w1 \! ~5 Z# H: v q[hide][/hide] |
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发表于 2012-11-10 12:55
发表于 2012-11-12 16:35
