PDF电子书：PROTEIN ENGINEERING （2012）

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PROTEIN ENGINEERING
* S% y/ u  o- SEdited by Pravin Kaumaya
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, }( g* Z$ J4 t/ M8 O7 T" O! UCopyright © 2012 InTech, z  z" Y2 b9 E5 X, a
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Contents8 m9 ]" `2 X* _; X" {  N
Preface   IX
9 _1 `, C1 C3 w$ Q; }/ u) T+ R; b/ B& mChapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1
# L- n# A0 ?: U5 @- x0 c3 EEduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. 3 q  D# m# \+ j  _3 _9 I
Arseniev) e  Z& H4 Q' }4 L& [* d  Z; p
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Chapter 2    Protein Engineering Methods and Applications   33
& }3 L! v$ q' \: Q0 c6 y1 OBurcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar0 P. p% L# A1 c+ s

+ o7 O1 V" G" g! u& cChapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino % [$ U& ?1 z# }4 i1 g& T
Acids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi; j* K1 k: B. W! y

, Q1 U2 }# M8 u, R; |( QChapter 4   Protein Engineering Applications on Industrially Important Enzymes:5 N6 T6 @; [0 h7 u9 }/ x
Candida methylica FDH as a Case Study    754 T+ d" J* v! J6 Z
Emel Ordu and Nevin Gül Karagüler
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0 S/ ~! h. i4 G4 e$ f7 H; C$ U& CChapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic 1 C. N# e) n, e0 v* g7 h& Q( ]
Targeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,
/ C+ u' H/ Z! k" s2 J& DK. Scott Weber, David L. Donermeyer,
4 J& d9 ^1 a3 F  Z# wPaul M. Allen, Roy A. Mariuzza and David M. Kranz/ `4 P$ z. B) y+ L2 _
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Chapter 6    Molecular Evolution Within; h7 D# H! S& \
Protease Family C2, or Calpains    119
2 T: f) z7 _5 ~; ]# C- WLiudmila Lysenko and Nina Nemova) |( X: N9 I3 O9 B) O" B4 V! z

. F) H. u1 ?7 `# r* S  m, pChapter 7    FN3 Domain Engineering   1452 q( h: j% M2 u. M
Steven Jacobs and Karyn O’Neil
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Chapter 8    Engineered Derivatives of- o9 I3 ~8 j! b, ?6 k
Maltose-Binding Protein   1630 K9 f' G' p; m4 q( k4 b9 q
Paul D. Riggs
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7 N. g( ]3 d) C* R* o& aVI     Contents4 j( o( z/ P" `  |* K( a5 Z! Y

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Chapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based " t3 {% \$ ~% t+ U+ m+ ~
Protein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky: I; f1 q# H8 ?! h2 u7 |. q
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Chapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207; Z4 m7 i8 R/ f+ Y% @; j
Shu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu
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* z9 K4 m( V& x( X  T" n+ GChapter 11    Protein Engineering with Non-Natural Amino Acids   253; ^: p- t% h* p8 n. t, _9 H
Aijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein* N- o2 c' |  y; M

; e/ h5 V# A2 E8 D9 gChapter 12    Generation of Xylose-Fermenting9 }& }+ m. q. {2 r8 V
Saccharomyces Cerevisiae by Protein-Engineering    291+ L6 O' c2 _7 y7 M' ]2 b" N+ r
Seiya Watanabe and Keisuke Makino
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Chapter 13   In Silico Engineering of Proteins
5 K, ?$ l. v' V! i% t- CThat Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela % W! k4 _9 R! p9 M7 ?
Wimmerová
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