PDF电子书：PROTEIN ENGINEERING （2012）

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$ o3 @% l8 Y  s) Q! Z# u& IPROTEIN ENGINEERING$ {" P& W; ]7 D
Edited by Pravin Kaumaya
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  n4 w; @3 M! ?- V9 KCopyright © 2012 InTech
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Contents
' q. g. ?, N  s, f8 GPreface   IX
; Z. Z7 c1 X. T" \Chapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1
- N5 U+ K# m. q8 T4 d  eEduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. * n4 v/ @; h. i* ?" p- M
Arseniev0 ]( Y  I. S4 D0 {9 Z
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Chapter 2    Protein Engineering Methods and Applications   33' n7 y' Q7 r) a. o5 L! u/ Z
Burcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar2 P: j/ A/ N6 U' b3 R
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Chapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino
+ w7 J0 \5 T! V: s% t# G+ f+ WAcids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi
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Chapter 4   Protein Engineering Applications on Industrially Important Enzymes:
9 V- B6 A+ y: x: \. UCandida methylica FDH as a Case Study    75% Q" V% Y5 H+ [; P5 x6 K- w# D
Emel Ordu and Nevin Gül Karagüler
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8 v. j; `0 U! K) e4 PChapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic
6 u7 j; o# K6 N& H6 m7 u+ d6 aTargeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,
) W+ q4 ~# E. s* T/ X9 ?6 u+ nK. Scott Weber, David L. Donermeyer,
5 k; H& Z! x4 y( _- v' A/ C% n' NPaul M. Allen, Roy A. Mariuzza and David M. Kranz7 s  {# ^7 p- D/ w

' ]2 \1 Z* |# FChapter 6    Molecular Evolution Within+ p& t' }  c: F0 b: U
Protease Family C2, or Calpains    119; M% ?# U6 {, \4 u. \5 {: J
Liudmila Lysenko and Nina Nemova8 |2 q) Z# B! b/ N, Q" x- p
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Chapter 7    FN3 Domain Engineering   145
6 r6 }# |4 H# e$ \8 g. nSteven Jacobs and Karyn O’Neil
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! a$ z2 v$ }. PChapter 8    Engineered Derivatives of( A9 O- O6 d" Q1 g9 ^4 A; I
Maltose-Binding Protein   163
$ g8 x1 b8 m+ G% `9 CPaul D. Riggs4 Y2 ~7 g( h3 ]5 U5 O% V

; u- U; }- M9 s  v3 OVI     Contents1 D( Z  @) D/ ~: h/ H9 B

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Chapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based
6 m- U, E' C' m' A, g7 I6 m* [/ HProtein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky
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  E' ^" c. ]! ^1 fChapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207* d$ t5 z; m$ n" y1 Q8 r7 _6 @
Shu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu' r  e' u6 ~8 M1 o, X: S3 r
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Chapter 11    Protein Engineering with Non-Natural Amino Acids   253
3 Q. G1 v+ b! m0 e# tAijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein
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Chapter 12    Generation of Xylose-Fermenting+ E' a& c# t' k% ]
Saccharomyces Cerevisiae by Protein-Engineering    2913 W6 z7 I0 s7 E/ ~- g5 Q
Seiya Watanabe and Keisuke Makino" U* X. p. H( R) a: |- a" B0 \& \
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Chapter 13   In Silico Engineering of Proteins
3 k5 j: g- w4 lThat Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela . u: y3 h. @6 h/ s3 V$ F" m
Wimmerová7 e$ W1 ?2 I: ]& `+ @9 S3 R

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