PDF电子书：PROTEIN ENGINEERING （2012）

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: f. Q8 D3 u" ]' f" y' e4 SPROTEIN ENGINEERING: [6 U6 `) P8 \8 D9 g# j
Edited by Pravin Kaumaya
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Copyright © 2012 InTech
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Contents5 ~4 C1 `( g/ H. ^' ~! o  D
Preface   IX; |. \) ?% ^5 ^# J  x* C
Chapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1
8 _; [" C- u1 f( TEduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. 1 j+ `7 {6 a% {2 x" C
Arseniev
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6 c& k6 T2 O( C& d) _3 a5 SChapter 2    Protein Engineering Methods and Applications   33
; t" J2 P( Y0 X7 U% y3 s% Z* jBurcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar% S  v! _7 t4 b  p" T2 v3 c
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Chapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino ( Q; Y  L$ c1 H, C" o) E
Acids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi9 B5 J3 N7 w2 f; V" X

4 I2 u7 s; a* [7 p# m% f% u; vChapter 4   Protein Engineering Applications on Industrially Important Enzymes:) y, o$ Z* G' L8 x' K3 L+ T4 K
Candida methylica FDH as a Case Study    75
6 }: x) K7 F6 G' Z0 q; XEmel Ordu and Nevin Gül Karagüler, F2 e% K# Z3 f" o  X( X5 P9 |0 N
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Chapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic 3 v. K1 _- F1 B7 B* D5 {
Targeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,& S7 e1 ~  n2 L- d3 H
K. Scott Weber, David L. Donermeyer,$ z; U+ g: d$ z5 w% o
Paul M. Allen, Roy A. Mariuzza and David M. Kranz4 d. A7 m: w. z9 H
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Chapter 6    Molecular Evolution Within+ s8 p- h9 H+ A3 s8 F$ i7 ]" V
Protease Family C2, or Calpains    119
# M. s1 S( j/ M4 T4 y" {9 xLiudmila Lysenko and Nina Nemova! m; Z4 s6 a% E/ J1 S
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Chapter 7    FN3 Domain Engineering   145$ x8 c5 J% L2 O: M$ l* h3 j
Steven Jacobs and Karyn O’Neil! Y. T) T+ y4 c  J9 \1 N* d
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Chapter 8    Engineered Derivatives of
: R" o/ u. x$ H0 x/ G: t' m4 ]Maltose-Binding Protein   163
6 d4 `3 }0 C6 t8 V/ e% p! gPaul D. Riggs
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4 h) {! d9 i3 ]. N4 N9 C$ qVI     Contents9 k- Y# `5 J/ A
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5 h3 {* S' ^: ?% I4 O) BChapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based 1 x/ R, f3 b7 u; I# K4 k
Protein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky
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Chapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207- i0 M7 H  ]! p5 P% s$ C
Shu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu
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Chapter 11    Protein Engineering with Non-Natural Amino Acids   253
0 H5 A- v: k% D# R& EAijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein* @  n) h- S2 O' L

, i' \# R. e$ EChapter 12    Generation of Xylose-Fermenting. a) J, {2 x3 g
Saccharomyces Cerevisiae by Protein-Engineering    291' B3 ]) X$ H, V9 m: c
Seiya Watanabe and Keisuke Makino. g* H1 g& f5 V2 Q

/ z! N6 z3 X4 h: Q7 fChapter 13   In Silico Engineering of Proteins
% d! U- @) `; s. u% eThat Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela
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