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Toxoplasma gondii infects the mouse gut and induces
5 [' a# |. j: ^3 Z: U# C5 man inflammatory response mediated by neutrophils that damages the intestinal
) x H' E0 [7 u. i1 }: [; P7 |tissue and leads to proliferation and translocation of commensal bacteria. In
5 B8 g5 K& t0 A/ Athis issue, Grainger et al. report that commensal bacteria help temper
0 u2 U$ \1 K" [* z4 G5 lthe inflammation caused by T. gondii by stimulating inflammatory Z- W' H, @* T* i) b2 @
monocytes to release prostaglandin E2, which dampens neutrophil activity. The
4 } i5 }" x' ^% `# n( c$ k% J9 bcover depicts commensal bacteria in blue and intestinal villi in red in mice
7 @6 C( S3 a# n, u, v, [* G5 Dinfected with T. gondii. Image credit: Lily Y. Koo and Michael J. Molloy. L, }) h/ _9 L9 B
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发表于 2013-6-8 20:34
发表于 2013-6-10 15:54
