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- 积分
- 17983
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- 17983
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- 26159
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Toxoplasma gondii infects the mouse gut and induces 2 B4 d! I; g# y7 h0 N
an inflammatory response mediated by neutrophils that damages the intestinal 5 B: E' a, T! B$ V: R1 d
tissue and leads to proliferation and translocation of commensal bacteria. In ' {* L9 Q% H3 l
this issue, Grainger et al. report that commensal bacteria help temper 8 l0 e7 ~- o/ S" U) c8 c
the inflammation caused by T. gondii by stimulating inflammatory 1 o, ^4 U ^& i' h: u, _
monocytes to release prostaglandin E2, which dampens neutrophil activity. The ! I0 s0 t3 {9 W% }1 O9 W' j
cover depicts commensal bacteria in blue and intestinal villi in red in mice ) W* Q- Z' ~6 x
infected with T. gondii. Image credit: Lily Y. Koo and Michael J. Molloy.
1 M: R5 Q' T X |* z+ R2 m$ g% ~# ?+ u+ Z. ]
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发表于 2013-6-8 20:34
发表于 2013-6-10 15:54
