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, k2 s, ?0 `1 ^1 y. O1 BToxoplasma gondii infects the mouse gut and induces ) i2 F+ Y3 T& U, b: E
an inflammatory response mediated by neutrophils that damages the intestinal % W: x" s4 V. F% i1 S8 Q
tissue and leads to proliferation and translocation of commensal bacteria. In 4 i2 A" ~. @9 N% G7 O- D* n; U
this issue, Grainger et al. report that commensal bacteria help temper
" Y p& D* c$ U# {! x/ Sthe inflammation caused by T. gondii by stimulating inflammatory
; m9 B# p2 U4 v+ \: L9 jmonocytes to release prostaglandin E2, which dampens neutrophil activity. The
& `- P# l# ^8 B, {' M9 G, ncover depicts commensal bacteria in blue and intestinal villi in red in mice $ {' C. X& c. f. w9 {
infected with T. gondii. Image credit: Lily Y. Koo and Michael J. Molloy.
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发表于 2013-6-8 20:34
发表于 2013-6-10 15:54
