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/ \. s% W; j& e) v7 L2 y% X$ TToxoplasma gondii infects the mouse gut and induces
- P3 @5 z* }4 N) J; U* Ean inflammatory response mediated by neutrophils that damages the intestinal
5 h7 P, M1 n9 ~4 X7 S8 _tissue and leads to proliferation and translocation of commensal bacteria. In
2 ?! A4 V! \. w8 B! u: q; {: tthis issue, Grainger et al. report that commensal bacteria help temper
4 w4 I' J8 b: @8 S# _the inflammation caused by T. gondii by stimulating inflammatory 3 V) r% I( x* h) u/ }$ b
monocytes to release prostaglandin E2, which dampens neutrophil activity. The ' n' |5 Q6 R$ V9 J' C
cover depicts commensal bacteria in blue and intestinal villi in red in mice 8 K2 j% W) F8 S$ ^0 {0 l t
infected with T. gondii. Image credit: Lily Y. Koo and Michael J. Molloy. 6 g; v- I+ z( Y1 L' r5 a3 l/ P
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发表于 2013-6-8 20:34
发表于 2013-6-10 15:54
