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- 积分
- 17983
- 威望
- 17983
- 包包
- 26159
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( t; y* R; \% u6 V; zToxoplasma gondii infects the mouse gut and induces - k' W, l& @ r" h' n
an inflammatory response mediated by neutrophils that damages the intestinal & u0 x4 r" I6 x0 Z1 \
tissue and leads to proliferation and translocation of commensal bacteria. In
2 \% l/ \+ Y2 B2 |. L/ Lthis issue, Grainger et al. report that commensal bacteria help temper
, U: G$ a& Y7 `2 h+ H( uthe inflammation caused by T. gondii by stimulating inflammatory - R1 y9 Q0 h3 l- @
monocytes to release prostaglandin E2, which dampens neutrophil activity. The $ N5 Q+ p9 c) L/ h: |
cover depicts commensal bacteria in blue and intestinal villi in red in mice
, x: G1 t1 k8 z, c4 Z5 ?: N8 binfected with T. gondii. Image credit: Lily Y. Koo and Michael J. Molloy. ^* G) J S0 {% b& B6 Z) k/ Y
& M! u5 q' g! \
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