|
- 积分
- 179
- 威望
- 179
- 包包
- 15
|
Cancer Res. 2013 Aug 2. [Epub ahead of print]
3 o' K2 D' A1 T7 V1 I+ k. \9 Tp63, Sharp1, and HIFs: Master Regulators of Metastasis in Triple-Negative Breast Cancer.$ X/ O3 [0 m/ k0 O7 J* p) F" e
Piccolo S, Enzo E, Montagner M.
# E/ h5 I3 U* j( ^3 S& W! YSource! Y& T( r8 S E
Authors' Affiliation: Department of Molecular Medicine, School of Medicine, University of Padua, Padua, Italy.+ ?' E# a! N! r6 E; [- Y# n
# ^7 h* K# m+ Y5 L2 |5 f8 ~5 H0 }8 s
Abstract
4 A& s# Z' Q+ Z+ V& RMetastasis is the most significant cause of cancer-associated morbidity and mortality but remains poorly understood. Recent work revealed that metastasis of aggressive triple-negative breast cancers is suppressed by Sharp1, a factor that promotes degradation of hypoxia-inducible factors (HIF) and blunts HIF-induced malignant cell behavior. Cancer Res; 73(16); 1-4. ©2013 AACR.
: V0 `. J6 i6 T$ ~% r2 p* u C' |2 d. w, b+ M( v
PMID: 23913939 [PubMed - as supplied by publisher]
( G5 J: _$ |- ?8 @. n9 vRelated citations |
|
发表于 2013-8-8 23:25
