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華盛頓9月4日(ANI)的研究人員已經發現了一個心臟發作後的心臟運動 ,一種方法與幹細胞的幫助下來重新同步心臟運動。
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! [. R* \% {# ^6 pWashington, Sept. 4 (ANI): Researchers have discovered a method to resynchronize cardiac motion following a heart attack with the help of stem cells.; {# ^3 g3 ~3 ?( b3 v
6 @2 H/ x: W8 HScientists implanted engineered stem cells, also known as induced pluripotent stem (iPS) cells, into damaged regions of mouse hearts following a heart attack. This regenerative approach successfully targeted the origin of abnormal cardiac motion, preventing heart failure.4 Y) o4 c2 a, }, o& a
5 n6 f* s; ^8 n, X' V9 R# GAndre Terzic, M.D., Ph.D., senior author of the study, said that the discovery introduces - for the first time - stem cell-based 'biological resynchronization' as a novel means to treat cardiac dyssynchrony.
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Muscle damage following a heart attack may disrupt normal heart conduction, resulting in a condition known as cardiac dyssynchrony.1 T: F3 o9 }! C0 B) {" {0 Z- o
3 _9 W4 s% M, y' X1 {Stem cell-based repair is going to offer a new solution to patients who would otherwise be resistant to device-based resynchronization.
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- n' `7 O: L/ a9 g2 O% CSatsuki Yamada, M.D., Ph.D., first author of the study, said that a high-resolution ultrasound revealed harmonized pumping where iPS cells were introduced to the previously damaged heart tissue.
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y' C3 I/ B3 l k) j* @The study provides evidence that a stem cell-based intervention may be effective in synchronizing failing hearts. Additional studies will follow to validate the value of stem cell-based regenerative solutions in addressing abnormal cardiac motion in heart failure, ultimately leading to improved patient care.
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The findings have been published in the Journal of Physiology. (ANI) |
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