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華盛頓9月4日(ANI)的研究人員已經發現了一個心臟發作後的心臟運動 ,一種方法與幹細胞的幫助下來重新同步心臟運動。6 v7 i% j: `3 M; u, C& L8 {
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Washington, Sept. 4 (ANI): Researchers have discovered a method to resynchronize cardiac motion following a heart attack with the help of stem cells.
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Scientists implanted engineered stem cells, also known as induced pluripotent stem (iPS) cells, into damaged regions of mouse hearts following a heart attack. This regenerative approach successfully targeted the origin of abnormal cardiac motion, preventing heart failure.4 s: A& b! Q. B4 P% m& J Z- X) L
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Andre Terzic, M.D., Ph.D., senior author of the study, said that the discovery introduces - for the first time - stem cell-based 'biological resynchronization' as a novel means to treat cardiac dyssynchrony.
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Muscle damage following a heart attack may disrupt normal heart conduction, resulting in a condition known as cardiac dyssynchrony.' |, q# y. j. B1 V, x
( P; A1 s9 _0 u1 zStem cell-based repair is going to offer a new solution to patients who would otherwise be resistant to device-based resynchronization./ d9 e; q0 k% s! R$ y* U: [& t' k
. Q: ]1 ], \. vSatsuki Yamada, M.D., Ph.D., first author of the study, said that a high-resolution ultrasound revealed harmonized pumping where iPS cells were introduced to the previously damaged heart tissue.* H( H: p) F8 z. W/ V' a
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The study provides evidence that a stem cell-based intervention may be effective in synchronizing failing hearts. Additional studies will follow to validate the value of stem cell-based regenerative solutions in addressing abnormal cardiac motion in heart failure, ultimately leading to improved patient care.
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" k3 h; n. z+ o+ _" s' B! [The findings have been published in the Journal of Physiology. (ANI) |
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