求助干细胞治疗多发性硬化文献一篇，急！

mantianfeiyun

各位大侠，紧急求助一篇文献，非常感谢！具体信息如下：
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1. Cell Transplant. 2014 Nov 5. [Epub ahead of print]
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4 E9 C$ g# D7 T, z, KThe potential of human umbilical cord-derived mesenchymal stem cells as a novel
/ P: m5 j9 s  S7 ]" Lcellular therapy for multiple sclerosis." Y1 P0 C2 \5 X

/ A1 j5 o4 s; Q5 a" H+ NLi JF, Zhang DJ, Geng T, Chen L, Huang H, Yin HL, Zhang YZ, Lou JY, Cao B, Wang
+ \. v& z9 t* n5 |6 B& lYL.3 A  }, p+ t3 U3 ?6 |

. k$ w/ |8 H4 HMultiple sclerosis (MS) is a complex disease of neurological disability,5 l, P; f( d5 h# j3 S. S
affecting more than 300 out of every one million people in the world. The purpose
0 I) F* T6 ?* ~; u! a: I$ _of the study was to evaluate the therapeutic effects of human umbilical1 L+ n* v3 E) R
cord-derived mesenchymal stem cell (hUC-MSC) transplantation in MS patients.
7 U/ h+ d9 K, w; F+ p7 HTwenty-three patients were enrolled in this study and 13 of them were given) j. [6 n  n0 U! m
hUC-MSC therapy at the same time as anti-inflammatory treatment, whereas the2 `* {" W% H, f. R/ t3 E( g
control patients received the anti-inflammatory treatment only. Treatment1 B$ |  h" p2 k  k1 t; S8 s
schedule included 1,000 mg/kg of methylprednisolone i.v. daily for 3 days and8 `( t4 g1 v, s$ A( f8 ~2 g
then 500 mg/kg for 2 days, followed by oral prednisone 1mg/kg/day for 10 days.
8 s" m' Z3 H% s2 a! ZThe dosage of prednisone was then reduced by 5mg every two weeks until reaching a
! \1 Z; Q+ }- U+ j2 T# o7 W5 ^( F5mg/day maintenance dosage. Intravenous infusion of hUC-MSCs was applied three
  O+ ^* v! r9 N0 y, utimes in a 6 week period for each patient. The overall symptoms of the hUC-MSC0 I: w; i* f5 e# z( R5 p- C
treated patients improved compared to patients in the control group. Both the7 @. L8 F. a$ D. ^. `
EDSS scores and relapse occurrence were significantly lower than those of the
" ?4 B4 |# R7 K. o9 T' Ccontrol patients. Inflammatory cytokines were assessed, and the data demonstrated
, @- ]+ j& g, Q. pa shift from Th1 to Th2 immunity in hUC-MSC treated patients. Our data2 Y, y: D8 Z  O
demonstrated a high potential for hUC-MSC treatment of MS. This manuscript is! t8 q  e7 i# Z% f
published as part of the International Association of Neurorestoratology (IANR)' K' e  T2 h8 ^, U
special issue of Cell Transplantation.' q- S& `& m$ y/ ]$ R0 R
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PMID: 25385295  [PubMed - as supplied by publisher], [$ j2 I  [! d, N

. P3 D% A! K2 X( S: c再次感谢！\(^o^)/~

benben52150

你需要的。。

mantianfeiyun

回复 benben52150 的帖子
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呵呵老兄，多谢热心帮助啊！但你提供的文献不是我想要的哦！
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我要的文章是2014.11新发的，Cell Transplant的，而你提供的文献是2011年发表于Stem Cell Rev and Rep的7 s4 r" W  |* ]6 y7 x
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不知能否继续帮我找2014年的这篇文献？再次感谢！

mantianfeiyun

回复 benben52150 的帖子1 Y2 K$ [! I$ W3 J, A5 e; I4 {
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不好意思，看错了，是我需要的文献，多谢多谢啊！

benben52150

mantianfeiyun 发表于 2014-12-3 09:17 ' o+ G( F) T. g: I' n  `7 W
回复 benben52150 的帖子1 D) S4 `' {8 y  X% b5 f
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不好意思，看错了，是我需要的文献，多谢多谢啊！

$ S3 F0 \' c; m客气