Mechanisms of Disease Cancer Stem Cells

richy

Craig T. Jordan, Ph.D., Monica L. Guzman, Ph.D., and Mark Noble, Ph.D.; B, H3 w; G3 C0 P0 R' x

, K+ X9 ?+ G) G* W9 @5 v! JThe deepening of our understanding of normal biology has made
& X9 B( y- b! \% ?4 jit clear that stem cells have a critical role not only in the generation of complex
  E1 j; Q$ ~" c7 D" W( Pmulticellular organisms, but also in the development of tumors. Recent
% `$ A0 S( t! r* o2 i, ffindings support the concept that cells with the properties of stem cells are integral( e  c4 e  [8 O. ^3 C
to the development and perpetuation of several forms of human cancer.1-3 Eradication* ^& J/ v. ?: j
of the stem-cell compartment of a tumor also may be essential to achieve stable,0 q. M! q1 X# b
long-lasting remission, and even a cure, of cancer.4,5 Advances in our knowledge of& S" F3 B; G" P1 L: d* n! U
the properties of stem cells have made specific targeting and eradication of cancer
5 J2 w( Y- w7 i+ R. Lstem cells a topic of considerable interest. In this article, we discuss the properties! I/ u$ v! a' ]0 z' e
of cancer stem cells, outline initial therapeutic strategies against them, and present
3 e& ~; W/ `- x! H4 _6 K3 Jchallenges for the future.
$ O9 Y$ f, i1 F, `
! x% o2 N8 ~. H0 Z; ?附件是ｐｄｆ全文  V4 U& q) z# Z# j  e
+ a! m+ a6 K$ K/ h" X9 @: b
[hide][/hide]

efool

不错，很有价值

Fischer3

好东西，要顶！

ahmusht

have a look

Chris

like it
4 u% A; m& J' J0 f8 e) `( gthanks

barton_nyd

好东西，看看啊

yolanda_sea

谢了

hualin840518

很好！

hualin840518

很好！谢谢诶！

15816126

good