Growth and trafficking

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Faulhammer et al. found that Sac1p localized to the ER during exponential growth and was retained there by a direct interaction with an integral ER membrane protein called dolichol phosphate mannose synthase, or Dpm1p. When the researchers transferred these fast growing cells to nutrient-poor media, Sac1p moved to the Golgi within minutes.
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3 y2 N7 O7 P( H( L6 SFrank Faulhammer, Gerlinde Konrad, Ben Brankatschk, Sabina Tahirovic, Andreas Kn?dler, and Peter Mayinger
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+ \0 o. c, K  D1 NJ. Cell Biol. 2005 168: 185-191.(The lipid phosphatase Sac1p inhibits tra)