请大家介绍一下在iPS方面比较牛的几位专家，谢谢！

michael1013

小弟对iPS比较感兴趣，想找些论文来读，所以烦请请大家介绍几位在iPS方面比较牛的专家，拜谢！

大刀无敌

日本的yamanaka 美国的   thomsen  中国 的 肖磊  周琦  裴端青 金颖

michael1013

谢了!

托斯卡纳教父

1.yamanaka------tokyo university
  _; ]! n  B/ Z8 |2.james thomson-----UW-madison
2 p% \7 T% f/ g/ ^. {; X6 Y3. daley& N" p# u- @! E1 K
4.janiesch

xjya

美国的Jaenish和Thomson4 X0 N% [/ v' L/ J
日本的Yamanaka

markllq

顶裴端卿！

ppcl2

回复 4# 托斯卡纳教父 : s8 X2 i/ D; t/ ?; ^2 [; t
山中是京都大学的，不是东京大学的。

daviehe

还有同济的裴刚！

chenks

广州的裴端卿,北大的邓宏奎,还有裴钢,周琪等,国外的就是楼上提到的Yamanaka, Jaenish和Thomson

kephort

在iPS领域发表最高影响因子的前几位科学家论文一览，附文献列表3 N2 E% h- ~+ g) s3 Y' ?
, t" i) V- s; _; t8 _! z. k1 v
REFERENCE LIST:
. w# w3 P9 E4 v( ~+ V6 k
, E! g' V% m/ L2 g6 E+ W. h; J
Daley, G. Q.        (9): e) L% [8 M5 R, y

4 N6 A- a+ S2 p. q: n: [! ^
8 X7 T" Z* K( B) @0 n5 T' J1.        Park, I.H., et al., Disease-specific induced pluripotent stem cells. Cell, 2008. 134(5): p. 877-886.$ [7 C  C, Z: p; u  U' L3 b0 k
2.        Park, I.H., et al., Generation of human-induced pluripotent stem cells. Nature Protocols, 2008. 3(7): p. 1180-1186.
3 S0 J; z: a. c; Z+ _3.        Ball, M.P., et al., Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nature Biotechnology, 2009. 27(4): p. 361-368.6 n% V" r% g2 l
4.        Loh, Y.H., et al., Generation of induced pluripotent stem cells from human blood. Blood, 2009. 113(22): p. 5476-5479.
4 g# \; [/ B2 e+ r5.        Chan, E.M., et al., Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nature Biotechnology, 2009. 27(11): p. 1033-U100.2 B: h9 A9 V5 Q2 ^3 t! f
6.        Doi, A., et al., Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nature Genetics, 2009. 41(12): p. 1350-U123.
& F8 k7 o, C. u  L) s4 Q$ C) R7.        Lengerke, C., et al., Hematopoietic Development from Human Induced Pluripotent Stem Cells. Hematopoietic Stem Cells Vii, 2009. 1176: p. 219-227.5 P- m0 r! x/ }
8.        Lengerke, C. and G.Q. Daley, Disease Models from Pluripotent Stem Cells Turning Back Time in Disease Pathogenesis? Hematopoietic Stem Cells Vii, 2009. 1176: p. 191-196.
( w3 f, J' v& k4 T# |9.        Sullivan, G.J., et al., Generation of Functional Human Hepatic Endoderm from Human Induced Pluripotent Stem Cells. Hepatology, 2010. 51(1): p. 329-335., i/ D& n7 R: u; w

9 D  N" P- T+ k% O, T- vHochedlinger, K.        (17)7 {' L3 l! R+ ?- H* a( \

8 n' K/ p0 W0 X! q3 M1 K
! }+ `3 R  ^9 @6 D+ v1.        Wernig, M., et al., In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature, 2007. 448(7151): p. 318-U2.# P) G7 P% w+ a' P- p
2.        Hyun, I., et al., New advances in PS cell research do not obviate the need for human embryonic stem cells. Cell Stem Cell, 2007. 1(4): p. 367-368.
6 ^' v- n5 r! B% z  \+ S3.        Maherali, N., et al., Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell, 2007. 1(1): p. 55-70.
/ T6 q# S" s6 p4.        Park, I.H., et al., Disease-specific induced pluripotent stem cells. Cell, 2008. 134(5): p. 877-886.
. @# q7 E' Y$ L" I5.        Stadtfeld, M., et al., Induced Pluripotent Stem Cells Generated Without Viral Integration. Science, 2008. 322(5903): p. 945-949.
3 Y7 L$ Y& y9 `1 p2 A* ^* p6.        Stadtfeld, M., K. Brennand, and K. Hochedlinger, Reprogramming of pancreatic beta cells into induced pluripotent stem cells. Current Biology, 2008. 18(12): p. 890-894.2 L% B7 Y' L% S/ p8 B% U
7.        Eminli, S., et al., Reprogramming of Neural Progenitor Cells into Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 Expression. Stem Cells, 2008. 26(10): p. 2467-2474.: n9 U3 ~" S/ F8 Y1 s
8.        Maherali, N., et al., A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell, 2008. 3(3): p. 340-345.
* _" v' E' {2 G9 @( F9.        Maherali, N. and K. Hochedlinger, Guidelines and Techniques for the Generation of Induced Pluripotent Stem Cells. Cell Stem Cell, 2008. 3(6): p. 595-605.
9 j6 \3 t" L% M5 Z10.        Utikal, J., et al., Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature, 2009. 460(7259): p. 1145-U112.
. q/ e0 _5 P+ f: @  e6 L11.        Sommer, C.A., et al., Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette. Stem Cells, 2009. 27(3): p. 543-549.
4 ^9 n' |3 X! U" C& N. k5 E- `12.        Eminli, S., et al., Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells. Nature Genetics, 2009. 41(9): p. 968-U29.
6 w% D  p1 v. u, u6 k13.        Utikal, J., et al., Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells. Journal of Cell Science, 2009. 122(19): p. 3502-3510.
: I. A$ k% j3 N! D  w* f8 t14.        Varas, F., et al., Fibroblast-Derived Induced Pluripotent Stem Cells Show No Common Retroviral Vector Insertions. Stem Cells, 2009. 27(2): p. 300-306.
( C4 _$ A6 r+ {# V1 s2 \15.        Maherali, N. and K. Hochedlinger, Tgf beta Signal Inhibition Cooperates in the Induction of iPSCs and Replaces Sox2 and cMyc. Current Biology, 2009. 19(20): p. 1718-1723.
! Y3 x1 F6 _, `7 J1 ?, B) _16.        Belmonte, J.C.I., et al., VIEWPOINT Induced pluripotent stem cells and reprogramming: seeing the science through the hype. Nature Reviews Genetics, 2009. 10(12): p. 878-U80.
, i% L! B, v$ Y" ~  x5 I17.        Stadtfeld, M., et al., A reprogrammable mouse strain from gene-targeted embryonic stem cells. Nature Methods, 2010. 7(1): p. 53-U10.
" _$ S' M' k% M4 X
3 b# E8 }# w7 yJaenisch, R.        (13)
# z0 Q7 h  Z) G* q( E# a1 m6 m+ I& q3 b: B3 k: o# Q. A4 T

8 t' d6 \4 Q  P3 q1.        Wernig, M., et al., In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature, 2007. 448(7151): p. 318-U2.2 [! h1 [1 A2 y" B$ r. H
2.        Hanna, J., et al., Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science, 2007. 318(5858): p. 1920-1923.
# x1 f: ^! t$ f1 Q2 Z4 X' \3.        Hyun, I., et al., New advances in PS cell research do not obviate the need for human embryonic stem cells. Cell Stem Cell, 2007. 1(4): p. 367-368.
+ n5 J( k, E" c4.        Maherali, N., et al., Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell, 2007. 1(1): p. 55-70.
" t8 E" y3 ]2 q4 s5.        Wernig, M., et al., Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America, 2008. 105(15): p. 5856-5861.
) o0 O# p; W2 B4 w6.        Wernig, M., et al., A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nature Biotechnology, 2008. 26(8): p. 916-924., U+ K/ v# b6 X, [: ^( h1 Z
7.        Eminli, S., et al., Reprogramming of Neural Progenitor Cells into Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 Expression. Stem Cells, 2008. 26(10): p. 2467-2474.
3 L4 p' U9 A8 v  @; I" l8.        Soldner, F., et al., Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell, 2009. 136(5): p. 964-977./ K/ G4 C$ d6 V3 N" Y4 I! c* X
9.        Lyssiotis, C.A., et al., Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proceedings of the National Academy of Sciences of the United States of America, 2009. 106(22): p. 8912-8917.! R+ Y3 Z8 ]5 M9 g
10.        Hockemeyer, D., et al., Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nature Biotechnology, 2009. 27(9): p. 851-U110.6 v9 S; K2 S" i; N( {) k* I
11.        Saha, K. and R. Jaenisch, Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease. Cell Stem Cell, 2009. 5(6): p. 584-595.
, r7 V  R& Z6 H* a& V/ I12.        Kuzmenkin, A., et al., Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro. Faseb Journal, 2009. 23(12): p. 4168-4180.) V$ ]: Z% h# I* N
13.        Carey, B.W., et al., Single-gene transgenic mouse strains for reprogramming adult somatic cells. Nature Methods, 2010. 7(1): p. 56-U12.0 X0 i- Q2 S8 g) d; U3 y3 r
8 C6 D3 T9 Y+ q/ T3 Z8 o* V9 u* |# k& ^6 e
Maherali, N.        (10)5 z- o7 o, p  {1 S7 Y) h, E

" H' t( }: i$ e& N6 c$ i6 }5 c9 ?8 m$ }- H7 X& H) d8 N2 k
1.        Maherali, N., et al., Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell, 2007. 1(1): p. 55-70.
. S( f" O3 g  d/ Q1 B' [- a2.        Park, I.H., et al., Disease-specific induced pluripotent stem cells. Cell, 2008. 134(5): p. 877-886.) g  P& |9 j; y5 W5 L
3.        Maherali, N., et al., A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell, 2008. 3(3): p. 340-345.
2 E9 Z! G; k" S+ p' }4 m" q& H4.        Maherali, N. and K. Hochedlinger, Guidelines and Techniques for the Generation of Induced Pluripotent Stem Cells. Cell Stem Cell, 2008. 3(6): p. 595-605.% u" }* O2 L' n. Z7 x
5.        Utikal, J., et al., Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature, 2009. 460(7259): p. 1145-U112.
2 A. m1 H* ?$ P& _6.        Eminli, S., et al., Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells. Nature Genetics, 2009. 41(9): p. 968-U29.  D9 |& Z3 S( W
7.        Utikal, J., et al., Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells. Journal of Cell Science, 2009. 122(19): p. 3502-3510.5 b4 q8 T4 v$ ]7 s1 U
8.        Varas, F., et al., Fibroblast-Derived Induced Pluripotent Stem Cells Show No Common Retroviral Vector Insertions. Stem Cells, 2009. 27(2): p. 300-306.9 S/ u$ U. P1 U: L3 h% E' @7 [
9.        Maherali, N. and K. Hochedlinger, Tgf beta Signal Inhibition Cooperates in the Induction of iPSCs and Replaces Sox2 and cMyc. Current Biology, 2009. 19(20): p. 1718-1723.
8 O% U6 @' C+ c" I6 {10.        Stadtfeld, M., et al., A reprogrammable mouse strain from gene-targeted embryonic stem cells. Nature Methods, 2010. 7(1): p. 53-U10.
  g: z. p9 P+ K# E* E) B) ~$ t( _! J
8 i& h9 F8 W! h' z0 |Okita, K.        (10)- S$ R; C: }0 _( X8 r) E) I
$ V1 ~# T5 l/ V, c

$ \2 J+ P7 R' l/ f. @1.        Okita, K., T. Ichisaka, and S. Yamanaka, Generation of germline-competent induced pluripotent stem cells. Nature, 2007. 448(7151): p. 313-U1.* G0 L: j! o! m9 w% z' m$ R. g
2.        Nakagawa, M., et al., Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nature Biotechnology, 2008. 26(1): p. 101-106.
. `6 z- ~! W( k3.        Okita, K., et al., Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors. Science, 2008. 322(5903): p. 949-953., H& O( n# L4 Z# x2 M3 L
4.        Narazaki, G., et al., Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation, 2008. 118(5): p. 498-506., \( D% [% F: u  q5 F! w  N4 Z  m
5.        Hong, H., et al., Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature, 2009. 460(7259): p. 1132-U95.
+ Y4 E' x+ L0 J5 |+ T0 ^# C- `0 q6.        Miura, K., et al., Variation in the safety of induced pluripotent stem cell lines. Nature Biotechnology, 2009. 27(8): p. 743-745.5 L$ A4 h8 j6 H6 y6 o
7.        Hirami, Y., et al., Generation of retinal cells from mouse and human induced pluripotent stem cells. Neuroscience Letters, 2009. 458(3): p. 126-131.
5 a4 {7 e; ?" h% D; E8 P7 o8.        Yoshida, Y., et al., Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells. Cell Stem Cell, 2009. 5(3): p. 237-241.
3 g2 T4 U" Y6 x% J+ c9.        Senju, S., et al., Characterization of Dendritic Cells and Macrophages Generated by Directed Differentiation from Mouse Induced Pluripotent Stem Cells. Stem Cells, 2009. 27(5): p. 1021-1031.
. r7 B" Q. {: M10.        Nishimura, K., et al., Transplantation of mouse induced pluripotent stem cells into the cochlea. Neuroreport, 2009. 20(14): p. 1250-1254.
4 S+ E+ N; i, M, q4 d5 b9 \7 T& Z* U- n) {, b! u! P
Park, I. H.        (9)
7 @( {$ M: M& R# T( H3 Q7 S" W( `; S

( [) o8 o% q" e8 |! C9 L1.        Park, I.H., et al., Disease-specific induced pluripotent stem cells. Cell, 2008. 134(5): p. 877-886.
/ |" }) z1 n# W2 @% n& y' Z2.        Park, I.H., et al., Generation of human-induced pluripotent stem cells. Nature Protocols, 2008. 3(7): p. 1180-1186.
) k  L9 i! u  N9 C* U+ p3.        Ball, M.P., et al., Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nature Biotechnology, 2009. 27(4): p. 361-368./ U9 ?/ `/ U6 }0 Z+ N
4.        Loh, Y.H., et al., Generation of induced pluripotent stem cells from human blood. Blood, 2009. 113(22): p. 5476-5479.
8 _1 A/ C7 o  o$ E1 O  J4 G5.        Chan, E.M., et al., Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells. Nature Biotechnology, 2009. 27(11): p. 1033-U100.
0 j9 `* x% G' \) B) {) V, ~6.        Doi, A., et al., Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nature Genetics, 2009. 41(12): p. 1350-U123.
' n* h3 w$ ?: `+ C2 k+ C7.        Lengerke, C., et al., Hematopoietic Development from Human Induced Pluripotent Stem Cells. Hematopoietic Stem Cells Vii, 2009. 1176: p. 219-227.8 n" X) n5 l1 H/ k0 `; T! h
8.        Zwi, L., et al., Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells. Circulation, 2009. 120(15): p. 1513-1523.
( p4 Z% j8 q% E+ E0 q& V+ P  ^9.        Sullivan, G.J., et al., Generation of Functional Human Hepatic Endoderm from Human Induced Pluripotent Stem Cells. Hepatology, 2010. 51(1): p. 329-335.
0 l: J* p& h7 s- L' l3 ^
0 l( H! x3 ^# ]- t4 gPlath, K.        (9)6 v' j, l/ G, H9 A3 O7 r* b" s

3 ?3 l& c7 A. J% e, ~) d7 L5 }4 z1 U7 C5 b4 T
1.        Maherali, N., et al., Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell, 2007. 1(1): p. 55-70.8 Q1 \! n2 \9 v5 r( {4 N" R
2.        Lowry, W.E., et al., Generation of human induced pluripotent stem cells from dermal fibroblasts. Proceedings of the National Academy of Sciences of the United States of America, 2008. 105(8): p. 2883-2888.% }4 G( c( q; K, R; \" z* P/ Z
3.        Schenke-Layland, K., et al., Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells, 2008. 26(6): p. 1537-1546./ Z* i+ e6 O% s2 ^8 o. ?  k3 t1 Z
4.        Lowry, W.E. and K. Plath, The many ways to make an iPS cell. Nature Biotechnology, 2008. 26(11): p. 1246-1248.
! z, s0 ^- Y+ n( v' [  p9 I" P5.        Chin, M.H., et al., Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures. Cell Stem Cell, 2009. 5(1): p. 111-123.
! l* A" A' F" Y( ~6 L2 e6.        Karumbayaram, S., et al., Directed Differentiation of Human-Induced Pluripotent Stem Cells Generates Active Motor Neurons. Stem Cells, 2009. 27(4): p. 806-811.
2 r  ]. e6 Q0 L4 ]! ?7.        Park, T.S., et al., Derivation of Primordial Germ Cells from Human Embryonic and Induced Pluripotent Stem Cells Is Significantly Improved by Coculture with Human Fetal Gonadal Cells. Stem Cells, 2009. 27(4): p. 783-795.
* U/ d: x: G6 M* C' l3 Y2 J6 ?8.        Xu, J., et al., Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells. Genes & Development, 2009. 23(24): p. 2824-2838.
% O2 w( \3 H/ W& r0 m! s5 g0 I# y  y1 Y9.        Hiratani, I., et al., Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis. Genome Research, 2010. 20(2): p. 155-169., L5 K1 @0 J0 M. g& Q: f2 j6 b0 y

& a- p1 {5 d* U9 i7 UStadtfeld, M.        (8)
% _8 m( f5 g9 {2 g0 U' [2 k: J2 @+ M/ w  z# r' u

( H% B" y& n" F3 j2 ^5 x0 g1.        Maherali, N., et al., Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell, 2007. 1(1): p. 55-70.7 b+ |1 S. y5 d" n
2.        Stadtfeld, M., et al., Induced Pluripotent Stem Cells Generated Without Viral Integration. Science, 2008. 322(5903): p. 945-949.
$ x7 G6 T# |) [, O! b6 y3.        Stadtfeld, M., K. Brennand, and K. Hochedlinger, Reprogramming of pancreatic beta cells into induced pluripotent stem cells. Current Biology, 2008. 18(12): p. 890-894.
0 e0 h: G% g+ h9 F8 E8 S2 R) u1 v4.        Utikal, J., et al., Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature, 2009. 460(7259): p. 1145-U112.) v, Q* T! ?0 P; V  w
5.        Sommer, C.A., et al., Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette. Stem Cells, 2009. 27(3): p. 543-549.# R, Y6 @; a7 {) h
6.        Eminli, S., et al., Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells. Nature Genetics, 2009. 41(9): p. 968-U29./ s7 h1 F; b6 z, E4 m, N
7.        Varas, F., et al., Fibroblast-Derived Induced Pluripotent Stem Cells Show No Common Retroviral Vector Insertions. Stem Cells, 2009. 27(2): p. 300-306.* ~8 X5 ]# U: T5 P( x% o! _0 @
8.        Stadtfeld, M., et al., A reprogrammable mouse strain from gene-targeted embryonic stem cells. Nature Methods, 2010. 7(1): p. 53-U10.
% ^4 U+ ^, Y' a* O/ x* s
# v5 _+ ?1 l9 `; d& t5 I, KTakahashi, K.        (9)9 a2 L1 J" h' I

4 L% x( \. ?( L# z$ F
* }* {3 h, a! t% }' ]1.        Takahashi, K. and S. Yamanaka, Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 2006. 126(4): p. 663-676.
$ z9 b; h0 m, z" L4 `2.        Nakagawa, M., et al., Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nature Biotechnology, 2008. 26(1): p. 101-106." R# R# `6 J  `+ S* u  T! _
3.        Hong, H., et al., Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature, 2009. 460(7259): p. 1132-U95.2 I' I' M  d7 H/ X* ~" m
4.        Miura, K., et al., Variation in the safety of induced pluripotent stem cell lines. Nature Biotechnology, 2009. 27(8): p. 743-745.
; n; D/ l( Q; n5.        Hirami, Y., et al., Generation of retinal cells from mouse and human induced pluripotent stem cells. Neuroscience Letters, 2009. 458(3): p. 126-131.3 ^7 i. [# n2 [& Q$ s, T
6.        Yoshida, Y., et al., Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells. Cell Stem Cell, 2009. 5(3): p. 237-241.2 {. o) _% L8 i9 {
7.        Taura, D., et al., Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells. Febs Letters, 2009. 583(6): p. 1029-1033.
! v% V1 Y" N9 s- K' i" B8.        Senju, S., et al., Characterization of Dendritic Cells and Macrophages Generated by Directed Differentiation from Mouse Induced Pluripotent Stem Cells. Stem Cells, 2009. 27(5): p. 1021-1031.
3 t' l5 F3 c! M; E0 A5 t' W9.        Taura, D., et al., Induction and Isolation of Vascular Cells From Human Induced Pluripotent Stem Cells-Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 2009. 29(7): p. 1100-1103.
* P6 c8 N0 ~* \1 ]
4 a" c* d) W2 M2 k6 G/ D' w0 fThomson, J. A.        (7)
& _) s% a1 `, O5 q3 c$ }  G0 |# L; s9 r

- H6 h5 E) s; D4 d7 F, i5 Q1.        Yu, J.Y., et al., Induced pluripotent stem cell lines derived from human somatic cells. Science, 2007. 318(5858): p. 1917-1920.4 _2 Y* u. E% ]
2.        Yu, J.Y. and J.A. Thomson, Pluripotent stem cell lines. Genes & Development, 2008. 22(15): p. 1987-1997.' h6 g8 p8 }9 F3 J% n7 ~
3.        Yu, J.Y., et al., Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences. Science, 2009. 324(5928): p. 797-801.
. a% T' Y+ \" B& I7 T" p9 {4.        Ebert, A.D., et al., Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature, 2009. 457(7227): p. 277-U1.6 V7 G  w5 |+ l7 e+ h+ n& t
5.        Zhang, J.H., et al., Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells. Circulation Research, 2009. 104(4): p. E30-E41.& N( m# b+ S+ _0 k) W" o% W0 M
6.        Lister, R., et al., Human DNA methylomes at base resolution show widespread epigenomic differences. Nature, 2009. 462(7271): p. 315-322.
1 `1 M+ r8 }. E' v( g1 ?8 e! O7.        Hu, B.Y., et al., Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proceedings of the National Academy of Sciences of the United States of America, 2010. 107(9): p. 4335-4340.( t/ @* ?  ~8 D: n: K' F
. F0 d; O* @9 u1 q" J& I
Yamanaka, S.        (20)
) a5 s' W) j/ b, \8 B. o2 k4 J4 F8 R. D- ^4 |
* Y5 _9 h  ~4 C, Y0 G
1.        Takahashi, K. and S. Yamanaka, Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 2006. 126(4): p. 663-676.
' W- t$ o* T  d$ t/ G9 L: _8 ?2.        Okita, K., T. Ichisaka, and S. Yamanaka, Generation of germline-competent induced pluripotent stem cells. Nature, 2007. 448(7151): p. 313-U1.2 j7 g# r) {  W. c4 p' G9 ~% N
3.        Hyun, I., et al., New advances in PS cell research do not obviate the need for human embryonic stem cells. Cell Stem Cell, 2007. 1(4): p. 367-368.
" F/ K% l* |' O) M* ?$ A# \( t3 S4.        Yamanaka, S., Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell, 2007. 1(1): p. 39-49.; e5 O) `- g+ C. {- P
5.        Nakagawa, M., et al., Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nature Biotechnology, 2008. 26(1): p. 101-106.
! J- |) ?9 W& k8 e6.        Okita, K., et al., Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors. Science, 2008. 322(5903): p. 949-953.2 R$ T- `8 I$ Z! ~4 Q
7.        Narazaki, G., et al., Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation, 2008. 118(5): p. 498-506.
) P% _) G& U1 P  J5 f2 {3 S8.        Yamanaka, S., Pluripotency and nuclear reprogramming. Philosophical Transactions of the Royal Society B-Biological Sciences, 2008. 363(1500): p. 2079-2087.
4 W1 k4 O( r4 w9.        Hong, H., et al., Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature, 2009. 460(7259): p. 1132-U95.9 Z! x% J4 S% B$ k2 F% N) L
10.        Miura, K., et al., Variation in the safety of induced pluripotent stem cell lines. Nature Biotechnology, 2009. 27(8): p. 743-745.7 e* m/ w1 q+ ]( E4 s3 ^& o  J
11.        Yamanaka, S., Elite and stochastic models for induced pluripotent stem cell generation. Nature, 2009. 460(7251): p. 49-52.. N+ _8 H: R& M1 L
12.        Hirami, Y., et al., Generation of retinal cells from mouse and human induced pluripotent stem cells. Neuroscience Letters, 2009. 458(3): p. 126-131.6 A' m& P' H6 l6 e
13.        Yoshida, Y., et al., Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells. Cell Stem Cell, 2009. 5(3): p. 237-241.* }! o# a( _" b9 e8 X) I! Y4 A
14.        Taura, D., et al., Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells. Febs Letters, 2009. 583(6): p. 1029-1033.
( ]. K2 H. {3 @  I' G: [15.        Senju, S., et al., Characterization of Dendritic Cells and Macrophages Generated by Directed Differentiation from Mouse Induced Pluripotent Stem Cells. Stem Cells, 2009. 27(5): p. 1021-1031.7 A" g+ ~* ]/ J% A" i
16.        Taura, D., et al., Induction and Isolation of Vascular Cells From Human Induced Pluripotent Stem Cells-Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 2009. 29(7): p. 1100-1103.
( {4 K( l# w+ L" t% y$ l17.        Tanaka, T., et al., In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochemical and Biophysical Research Communications, 2009. 385(4): p. 497-502.
8 h/ X, _' g0 {  a18.        Yokoo, N., et al., The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells. Biochemical and Biophysical Research Communications, 2009. 387(3): p. 482-488.
, `$ y9 v& L" b* j/ L# s- P19.        Nishimura, K., et al., Transplantation of mouse induced pluripotent stem cells into the cochlea. Neuroreport, 2009. 20(14): p. 1250-1254.+ E. o( Z2 c* V/ y. k/ }) J( L" E
20.        Belmonte, J.C.I., et al., VIEWPOINT Induced pluripotent stem cells and reprogramming: seeing the science through the hype. Nature Reviews Genetics, 2009. 10(12): p. 878-U80.