- 积分
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- 1030
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histone H3
/ h. p m3 p h! gmethylation at lysine 9 is associated with heterochromatin and
, H) M1 j h! Y' qgene silencing, while histone H3 at lysine 4 or 27 is associated
5 ]! @0 [9 {& Q+ p/ L. ^7 l+ H0 S% Cwith transcriptional activation.
: R6 y6 D1 c R2 B# o1 [
7 H# m- s5 A& X/ k+ rEach lysine residue may be
3 a+ J5 h/ M" q$ n2 dmethylated in the form of mono-, di-, or tri-methylation, adding
' F" i" N' ~3 P* Z) @: Aenormous complexity. Deciphering histone tail modifications
' [8 z5 \1 x) M5 e* s ^and defining a potential “histone code” controlling gene expression( y% }0 _0 v N) l; u5 J5 x% B% A
represents an emerging field of epigenetic research 。( R2 w/ \' ?% P: b9 g
Whether the potential histone code is modifiable by environmental5 C& @' n6 Y: D/ f+ L+ _# ^/ j7 z
exposures, similar toDNAmethylation patterns, remains
7 m; t, `; j5 {to be determined.
( F" W0 T5 `" U可以的话请把汉语写下来,谢谢。里面有些术语我都不知道翻成什么。 |
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