《细胞》[Cell]12年5月11日出版pdf全文

zorro

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      On the cover: Nuclear pore complexes (NPCs) have long been assumed to be the sole gateway for macromolecular transport in and out of the nucleus. Speese et al. (pp. 832–846) provide evidence that, during Wnt-regulated synapse development, large ribonucleoprotein (RNP) granules carrying postsynaptic mRNAs are exported out of the nucleus through an alternative mechanism. The granules bud through the nuclear envelope. Although this mechanism has been previously demonstrated for the nuclear egress of herpes-type viruses, Speese et al. now suggest that exit through nuclear envelope budding is an endogenous mechanism for the export of large RNPs. The drawing, “Searching the way out of the nucleus,” represents a long journey through “brainscapes,” searching for a route out of the postsynaptic nucleus. In the end, the only way out was budding across the nuclear envelope. Ink drawing by Vivian Budnik, modified using ImageJ software% t9 W8 Y8 L! J" H% L
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owenlion

first time to see see2 g+ K) M7 Z) Y( z, d* T

懵懂干细胞

谢谢楼主分享 分享万岁

191225092

CELL！！！好期刊！！！

manybit

看看

zxcv12345

谢谢

Eul_er

权限不够，虽然很想看。

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490096812

我邮箱490096812@qq.谢谢了

不倒翁

谢谢分享( b3 Z7 \) a0 T" Z# V. ?