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本帖最后由 细胞海洋 于 2013-2-21 10:11 编辑 5 w1 x- w( Q/ U; J
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Book Title
9 d0 _) w( E$ b+ O* oStem Cell Engineering
: w' U! X3 M2 L( P5 J) |; OBook Subtitle
; `9 W% w3 \+ }/ G+ ~' L. vPrinciples and Applications
0 ^& K5 f+ F- T! c' nCopyright- k/ h" g6 F7 c% f& d
2011
" L2 m& n. i' L% ADOI# j( V1 T, b0 L ^ R: M# ~: z
10.1007/978-3-642-11865-4
c4 J" v |! LPrint ISBN+ u( [3 E1 d, n
978-3-642-11864-7* V b6 a4 H1 _. k9 I' a
Online ISBN
: K; m* V0 u1 ?" p978-3-642-11865-4
3 Z3 u: T& R. u' `$ Q, WPublisher
& N! b. n3 E$ R" l U- w3 jSpringer Berlin Heidelberg3 x& k! c8 ]! u& \
Copyright Holder) u$ a6 [! p3 \$ U: I
Springer-Verlag Berlin Heidelberg+ c. E$ ~6 E! F5 g" _
$ \$ ~% m- c7 C+ Q ~- Reviews Engineering Approaches in Stem Cell Research
' k- a# G2 N( g T' s- Provides a solid reference for researchers and advanced graduate student9 O7 v' H) M) H) ~$ w( P
The potential of stem cells for healing and disease prevention in all fields of medicine is tremendous and has revolutionized the high-tech biomedical research. In this book, many of the most prominent researchers discuss the challenging topics of stem cell engineering, for example: Ethical issues of stem cell research; technological challenges, stem cell growth and differentiation, therapeutic applications, bioreactors and bioprocesses, high throughput and microfluidic screening platforms, stem cell identification and sorting, intercellular signaling and engineered niches, novel approaches for embryonic and adult stem cell growth and differentiation, stem cells and drug discovery, screening platforms. Stem Cell Engineering offers valuable background and reference for both the public and professionals including industrial staffers, faculty, researchers, engineers, students and scientific journalists.2 W4 e* k% V% p/ g) D
Content Level » Research
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Keywords » bioreactors - cell expansion - differentiation - drug discovery - embryonic stem cell growth - stem cell growth
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Related subjects » Biomedical Engineering - Biotechnology - Cell Biology3 o9 N# L, `/ F3 `0 G
$ `1 ?1 t; z4 P4 j* C$ f* H6 q( ZContents) {& d0 ]$ c' I3 x5 y
Part I Instead of an Introduction – The Emperor’s New Legs, ^- I9 J9 C. J2 T" T. k4 [
The Emperor’s New Body: Seeking for a Blueprint of Limb3 B3 S- r$ o+ \$ m
Regeneration in Humans . . . . . . . . . . . . . . . . . . . . . . . . . . 3+ r' ?& v. G- [; P% w+ K2 o
Ilya Digel and Aysegül Temiz Artmann
* ` J" I! B! s" i* Y% iPart II Basics and Basic Research( I" R% ]: @2 d7 H3 {
Engineering the Stem Cell Niche and the Differentiative Microand
$ u5 I& q+ p. H, n/ QMacroenvironment: Technologies and Tools for Applying
1 u1 N( i) `( vBiochemical, Physical and Structural Stimuli and Their Effects
& I7 z* ^* g1 K8 m; \( gon Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
' I5 K0 b" J1 o' {) d& ?. w6 Z- DPaolo Di Nardo, Marilena Minieri, and Arti Ahluwalia- k9 N4 j- \& S) }, W* }# c) @! d
Differentiation Potential of Adult Human Mesenchymal Stem Cells . . 611 h6 t* ~4 U- S% i
Edda Tobiasch
, }3 J4 k- h6 i! ?The Potential of Selectively Cultured Adult Stem Cells. D$ V! J* c' q8 D( Q' a9 s" c: V x
Re-implanted in Tissues . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
u" x) F0 f; N# q. j5 s* }9 c# ]# ~Isgard S. Hueck, Martin Haas, Rita Finones, Jane Frimodig,
- ?5 L6 { M+ m, g8 o% y/ zand David A. Gough% ?3 m+ M% G6 Y! h# O
Enhanced Cardiac Differentiation of Mouse Embryonic Stem
9 g% p' `8 G: m/ E+ l8 rCells by Electrical Stimulation . . . . . . . . . . . . . . . . . . . . . . . 1195 }7 m( j# T6 u& g! n
Paul R. Bidez III, J. Yasha Kresh, Yen Wei, and Peter I. Lelkes
6 x1 C& i% g& c Y& y+ C/ q+ w& J# \The Therapeutic Potential of ES-Derived Haematopoietic Cells . . . . . 143( I' F, g1 l2 g! ~ e2 D
Sabrina Gordon-Keylock and Lesley Forrester; T" t/ S, j& J. C6 {
Genetic Modification of Human Embryonic and Induced. C+ y$ C$ f, ^$ `# y5 F m
Pluripotent Stem Cells: Viral and Non-viral Approaches . . . . . . . . . 159
8 g' x# y" ]& ~' z5 h" ~Nicole M. Kane, Chris Denning, and Andrew H. Baker
, r% P" o3 Z1 Q0 T) OThe Immune Barriers of Cell Therapy with Allogenic Stem Q$ u, Y1 @& R* N3 D; v* e! @
Cells of Embryonic Origin . . . . . . . . . . . . . . . . . . . . . . . . . 181
* m4 ?+ }2 Q9 a" t0 O W5 lOlivier Preynat-Seauve, Karl-Heinz Krause, and Jean Villard0 |. E5 L& J7 F. @3 F( Y, i. F
xxxi: Q8 K5 d8 h& K$ y: [
xxxii Contents
8 k- B* h8 `4 Z) f( }Reponses of Mesenchymal Stem Cells to Varying Oxygen0 N/ S+ U, t6 @2 }
Availability In Vitro and In Vivo . . . . . . . . . . . . . . . . . . . . . . 199( P& o# h& K; g3 Y2 k* |
Frank R. Kloss, Sarvpreet Singh, and Günter Lepperdinger
+ ?5 ]% d: R2 j% M$ L Y* LEndothelial Progenitor Cells and Nitric Oxide: Matching
$ R5 E5 `% Q0 c5 V8 O7 G6 _6 |Partners in Biomedicine . . . . . . . . . . . . . . . . . . . . . . . . . . . 213: m3 b! u, M$ l5 P& a
Stefanie Keymel, Burcin Özüyaman, Marijke Grau, Malte Kelm,! ?" Z+ o: G. X' I& g
and Petra Kleinbongard
# J, f3 J( i- F8 ^* O# P# iSkeletal Stem Cells and Controlled Nanotopography . . . . . . . . . . . 247" c4 l! [! {9 G3 G( a1 k
Matthew J. Dalby and Richard O.C. Oreffo* V9 m3 Y# y$ @6 j0 q ~* M% }
Part III Clinical Applications! C0 |* O. K- r; D& b9 P- m$ l
Cells and Vascular Tissue Engineering . . . . . . . . . . . . . . . . . . . 261! T" N1 V2 F) n' R6 _: \/ X
John Paul Kirton, Tsung-Neng Tsai, and Qingbo Xu
0 @+ n, L t2 t6 P; MEndothelial Progenitor Cells for Vascular Repair . . . . . . . . . . . . . 297
9 R p/ E' Y5 J# c1 P5 uMelissa A. Brown, Cindy S. Cheng, and George A. Truskey9 f; N! g2 ]# L+ ]) ?6 s
Regenerating Tubules for Kidney Repair . . . . . . . . . . . . . . . . . 321
8 I, U1 l7 n, IW.W. Minuth, L. Denk, and A. Roessger8 t" | h& d# w
Stem Cells in Tissue Engineering and Cell Therapies
3 i0 e( u: W3 d" e {2 l3 Hof Urological Defects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345/ j3 x6 }( ^4 b0 e. X
Christoph Becker, Katrin Montzka, and Gerhard Jakse9 l; p: }2 R# r; f
Bio-synthetic Encapsulation Systems for Organ Engineering:
) @+ [+ R$ b3 m. [/ Q: QFocus on Diabetes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363
H7 |9 w5 @3 F& \Rylie A. Green, Penny J. Martens, Robert Nordon,$ l* X* c6 I0 X& l. p) k* m
and Laura A. Poole-Warren& P3 ^* q) w! W* P: ^/ P" [! J# M( }
Stem Cell Engineering for Regeneration of Bone Tissue . . . . . . . . . 383
3 E- Z1 N9 r; p5 b& a# W$ t% \Michael Gelinsky, Anja Lode, Anne Bernhardt, and* A2 s M: b+ o( a* N- L
Angela Rösen-Wolff1 e5 ]' |3 s; @" e3 Z* z; O
Part IV Techniques and Applications
! R$ W. n2 ]. C4 C* VBuilding, Preserving, and Applying Extracellular Culture
' G, K: `, ^9 ], x& n1 TIntegrity Using New Cell Culture Methods and Surfaces . . . . . . . . . 403
4 _" @# V7 y0 Z5 ]# x7 c7 G/ KThomas Brevig, Robin Wesselschmidt, and Masayuki Yamato% L$ P! n# W5 |% k; \5 I- y
Fabrication of Modified Extracellular Matrix
! f- `% r h. Y/ v. C2 c4 F& qfor the Bone Marrow-Derived Mesenchymal Stem Cell! J& G& Z1 M* o4 E+ Q
Therapeutics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4173 T2 L; k+ O) I
Hwal (Matthew) Suh
6 _! S; h1 d: k3 B) g& ]Neural Stem Cells: From Cell Fate and Metabolic Monitoring, F9 [ D2 N* a+ [! Y
Toward Clinical Applications . . . . . . . . . . . . . . . . . . . . . . . . 435
3 h0 m, C. C: C1 l1 R7 |$ W Z- n M$ cJan Pruszak, Máté Döbrössy, Jochen Kieninger, Kuppusamy
; y6 A+ v, g0 C$ Q; O; @/ B3 rAravindalochanan, Gerald A. Urban, and Guido Nikkhah
, [ s) h1 A' m7 @& |Contents xxxiii1 ^$ b3 _8 i( L: y, X
Adult Stem Cells in Drug Discovery . . . . . . . . . . . . . . . . . . . . 457
# [ ]* e) Z% Z7 ?Stefan Golz, Andreas Geerts, and Andreas Wilmen0 ]! n- ]/ g( K4 T
Embryonic Stem Cells as a Tool for Drug Screening and Toxicity Testing 4731 t5 V. u8 ?. \+ Z
Bernd Denecke and Silke Schwengberg
9 A1 X% }5 Q3 k3 QEmbryonic Stem Cells: A Biological Tool to Translate the
0 a& C0 O( K3 q; ]9 LMechanisms of Heart Development . . . . . . . . . . . . . . . . . . . . 501
; W3 H1 }5 o p/ o# UOmonigho A. Aisagbonhi and Antonis K. Hatzopoulos
: o4 d6 }, a0 EIndex . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521 |
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