[全文]丁盛Nat Methods新文章－－提高iPS诱导效率200倍

芷瞻

Nat Methods. 2009 Oct 18.【Epub ahead of print】
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A chemical platform for improved induction of human iPSCs.7 U; [) i6 k- M) p

5 {: G; l. w# \Lin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, Lin X, Hahm HS, Hao E, Hayek A, Ding S.
2 D. u' Y! {; n3 F8 @2 eDepartment of Chemistry, The Scripps Research Institute, La Jolla, California, USA.4 B: m4 B- @( N6 w9 F8 J, ]
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The slow kinetics and low efficiency of reprogramming methods to generate human induced pluripotent stem cells (iPSCs) impose major limitations on their utility in biomedical applications. Here we describe a chemical approach that dramatically improves (200-fold) the efficiency of iPSC generation from human fibroblasts, within seven days of treatment. This will provide a basis for developing safer, more efficient, nonviral methods for reprogramming human somatic cells.! W  y, T' n- h" V1 S$ h3 `

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jianlindunev

学习中，感谢

好玩301

怎么下载不了了？仍然感谢

sunyucheng

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应菜

能下，谢谢

lorey

顶！好文章

dengyanfei

非常感谢

carolshf

非常感谢

风源

感谢

mmssyyee

请问你有没有这篇文章的methods呀？我在网上下载不了，有的话能不能给我一份啊，谢谢！！！