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- 积分
- 118
- 威望
- 118
- 包包
- 43
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首先1、肿瘤是个复杂系统性的病?
4 r+ x0 G1 J8 ~其次2、这就难怪为何会有如此多的肿瘤假说模型能立一家之言,其必有接近真理的一面,但太局限
) a* U7 v5 o4 k, B# hIt is possible that the number of different tumor types is equal to the number of patients.
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y/ `% L8 S: O2 G/ z2 B2 o再次3、反应了肿瘤是个需要通盘考虑的、不能仅仅局限于点、线(癌基因、肿瘤干细胞、多倍体)上的考虑、是否能集众家之长?剔伪存真
. j' Y7 {/ l, x; {# B" O( l) f( Pthe cancer stem cell theory is just playing with concept. Cancer is due to the failure of developmental (proliferation) control. The key is the mutation of genes, and epigenetic maintenance. 2 D5 X/ q7 x5 u) n- R
* A3 L6 a& a3 ^ t4、繁琐复杂现象的背后、必有其本质;不要急于求解现象本身,更应该追溯其本质;如果你抓住的是本质,应该适用于所有的肿瘤和解释所有现象,有本及末,方有头绪。
: h/ ]2 t1 f# Q8 v3 s- g+ j5、你可能会发现,肿瘤可能比人预想的要复杂的多得多!/ d/ W: }; e2 h0 T' |
I believe that we already understand at least 50% of the mystery. we just don't know how to rationally design drugs like gleevec. |
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