Embryonic Stem Cell Lines Derived from Human Blastocysts

ng_pan

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5 P. ^0 K0 w9 h( n' \Embryonic Stem Cell Lines
" u( {% a1 P6 b4 K: e; k# |Derived from Human
" E8 V" {. E) ZBlastocysts" \; D3 x3 H8 Q' u" u
James A. Thomson,* Joseph Itskovitz-Eldor, Sander S. Shapiro,4 N' H7 L) I7 B
Michelle A. Waknitz, Jennifer J. Swiergiel, Vivienne S. Marshall,5 r7 R1 C; L  E9 T
Jeffrey M. Jones
. c+ S& s% ~1 w8 ^5 dHuman blastocyst-derived, pluripotent cell lines are described that have normal% ?0 A, i! d5 O. L" x/ Q1 N) R
karyotypes, express high levels of telomerase activity, and express cell surface) J* C1 [# k% V: _
markers that characterize primate embryonic stem cells but do not characterize
, i" p  c: |" j" c, ]* Iother early lineages. After undifferentiated proliferation in vitro for 4 to 5
1 o+ p. c( ]8 H& T0 umonths, these cells still maintained the developmental potential to form trophoblast
) I8 F" G; ]: X, f; l. Z" sand derivatives of all three embryonic germ layers, including gut: B" Z* S% A: B. c& h3 x8 _
epithelium (endoderm); cartilage, bone, smooth muscle, and striated muscle# l6 C# [- t. r1 d5 k
(mesoderm); and neural epithelium, embryonic ganglia, and stratiÞed squamous
, b+ Z  h8 J& [9 q4 v. ~epithelium (ectoderm). These cell lines should be useful in human developmental( y2 |" _& D- G+ e
biology, drug discovery, and transplantation medicine.
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tspaulzhao

Thanks.

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张也行

哈哈 Thomson教授的书啊！谢谢LZ分享！

zhaokai

急需，感谢

xiaoheilong

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大漠

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kim22222

谢谢

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