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本帖最后由 细胞海洋 于 2010-5-21 06:54 编辑 ( C$ ^/ ]# _" f/ e5 H% X: F6 j7 [
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李凌松*，王 莉
' Q' [1 F: d. g4 |" \' V) b（北京大学干细胞研究中心细胞生物学系，北京 100871） Z$ x6 u% K$ o! A: }* @
摘 要：胚胎干细胞具有自我复制并分化为人体各种功能细胞的潜能。胚胎干细胞具有的独特生物学/ {2 U+ n1 @0 v9 [/ S/ b$ X
特性使其被广泛应用于生物学研究的各个领域，特别是发育学。同时，它潜在的医学应用也成为世界
6 e" k' z" d* S5 t \范围内的研究热点。但是，由于人胚胎干细胞的来源为植入前的早期胚胎，人胚胎干细胞自诞生之日
3 ~0 c# Y1 U: o$ [# `& s起便倍受争议。本文将从胚胎干细胞的来源、特性、鉴定标准、增殖机理、应用前景以及研究本身- A' q3 T3 M1 E# k" o! p
涉及的伦理学争论给予概述。' G6 X2 m; z" `5 Z4 @
关键词：胚胎干细胞；自我更新；分化；鉴定；胚胎生殖细胞；应用
R1 O( V" z% c. `: h中图分类号：Q813 文献标识码：A
1 I+ W' c2 Z4 O) E x& TEmbryonic stem cells+ i, m" t' F- n9 [- F/ r
LI Ling-Song*, WANG Li- A* `6 B7 F. J' q
(Department of Cell Biology, Stem Cell Research Center, Peking University, Beijing 100871)
5 a \3 u8 _2 sAbstract: Embryonic stem (ES) cells are able to self-renew and differentiate into all kinds of human cells. Due to
0 K" J# r0 u" Htheir unique properties, ES cells are used in diverse fields of biological research，particular in developmental
- r8 q* U+ d; D+ U' ?6 `biology. Meanwhile, their potential medical application become a research hot-spot worldwidly. Since preimplantation( b$ u4 E( w0 g/ x. s
eggs are sources to generate ES cells, the use of embryonic stem cells is therefore controversial.3 C) N3 t; k2 [' w/ l' T4 Q2 L# {6 S* K
This review will outline characterization of ES cells, regulation of self-renewal, and the applications of the cell) d7 w! \/ n. ?/ t8 V
in treating diseases, as well as ethical issues related to human ES cells research." r: N/ E/ l1 x
Key words: embryonic stem cells; self-renewal; differentiation; characterization; embryonic germ cells;1 M$ P- ]: P& ^6 |- z' H
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发表于 2009-2-27 10:29
发表于 2009-7-14 15:44
