The stem-cell niche as an entity of action

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Stem-cell populations are established in ‘niches’ — specific anatomic locations that regulate how they
3 t: R0 H. V1 C+ @# @participate in tissue generation, maintenance and repair. The niche saves stem cells from depletion,
. B4 _4 \' A- g& Bwhile protecting the host from over-exuberant stem-cell proliferation. It constitutes a basic unit of tissue  i- J2 U  E, V8 z  H
physiology, integrating signals that mediate the balanced response of stem cells to the needs of organisms.8 V! C0 y) g* Q3 e3 R
Yet the niche may also induce pathologies by imposing aberrant function on stem cells or other targets. The
' x) ?7 B  o% z" B# g5 ?& l2 binterplay between stem cells and their niche creates the dynamic system necessary for sustaining tissues, and
: g* s# s/ y( K8 Y+ a2 hfor the ultimate design of stem-cell therapeutics.

张也行

十分感谢  楼主最近好慷慨啊

张也行

十分感谢  楼主最近好慷慨啊

changylin

感谢

ywna917

十分感谢啊！