The stem-cell niche as an entity of action

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Stem-cell populations are established in ‘niches’ — specific anatomic locations that regulate how they
, b. d$ y6 D" `& x9 Z: Lparticipate in tissue generation, maintenance and repair. The niche saves stem cells from depletion,, ~2 B' R1 |8 i3 C- v& r. o
while protecting the host from over-exuberant stem-cell proliferation. It constitutes a basic unit of tissue
/ Z. o% {$ \  {+ a' p# Rphysiology, integrating signals that mediate the balanced response of stem cells to the needs of organisms.
' E% Q& k" A" }4 M4 E; N5 LYet the niche may also induce pathologies by imposing aberrant function on stem cells or other targets. The
$ [) F+ {, j6 j( Ainterplay between stem cells and their niche creates the dynamic system necessary for sustaining tissues, and
  T4 J% o, x: G. y# }; nfor the ultimate design of stem-cell therapeutics.

张也行

十分感谢  楼主最近好慷慨啊

张也行

十分感谢  楼主最近好慷慨啊

changylin

感谢

ywna917

十分感谢啊！