The stem-cell niche as an entity of action

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Stem-cell populations are established in ‘niches’ — specific anatomic locations that regulate how they
4 t/ y/ g2 O* x0 O$ l' [* Vparticipate in tissue generation, maintenance and repair. The niche saves stem cells from depletion,
) r3 W9 m. `1 N8 u2 Cwhile protecting the host from over-exuberant stem-cell proliferation. It constitutes a basic unit of tissue8 d- d" l! o1 x1 E1 H9 M3 K
physiology, integrating signals that mediate the balanced response of stem cells to the needs of organisms./ K+ F$ H" J$ X0 T7 l. X8 c
Yet the niche may also induce pathologies by imposing aberrant function on stem cells or other targets. The
# h; i5 e# ^( D0 ^! ]% Yinterplay between stem cells and their niche creates the dynamic system necessary for sustaining tissues, and' P1 Q; J! H" }  B( i1 Y6 K# @3 d
for the ultimate design of stem-cell therapeutics.

张也行

十分感谢  楼主最近好慷慨啊

张也行

十分感谢  楼主最近好慷慨啊

changylin

感谢

ywna917

十分感谢啊！