|
- 积分
- 2314
- 威望
- 2314
- 包包
- 5399
|
 
分化但未观察到疾病表型的：' w" N: K0 |& `, m6 Q
1. Dimos, J.T. et al. Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons. Science 321, 1218-1221 (2008).9 V7 i7 T) R+ G6 L0 I4 E. z: o1 P
神经疾病：7 j- m6 n- G" X8 W8 c
2. Park, I.-H. et al. Disease-Specific Induced Pluripotent Stem Cells. Cell 134, 877-886 (2008)." m ^6 S" }" V3 {1 s. r& h; \9 V$ k
神经疾病：
2 o8 d4 c5 \* p# k3. Soldner, F. et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell 136, 964-977 (2009).
/ K4 S) k4 [1 m/ x# I: O神经疾病：
/ t1 X: K/ Z; k2 s/ ~" s4. Maehr, R. et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proceedings of the National Academy of Sciences 106, 15768-15773 (2009).
) p. e3 ]* p0 K1 `4 K糖尿病：
2 K; w1 w0 c9 ^& ?5. Ye, Z. et al. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114, 5473-5480 (2009).! ~" J6 s5 |9 E$ D0 T5 `
血液疾病：, V5 C8 w' H7 D$ Y$ W( Y
6. Yang, J. et al. Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader-Willi syndrome. Journal of Biological Chemistry.) }8 o" a- k4 f; A
genomic imprinting disorder：* C. u7 y$ L/ _- A: k {9 D; D
- ^. S- b1 _& b ^' i' D3 M9 ]! W3 C' j Y$ ^) }0 r3 w( B7 ?
成功观察到疾病细胞表型的：* Z7 `4 V* Z+ p
7. Ebert, A.D. et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-280 (2009).
3 y7 G0 w6 p- O7 L4 B神经疾病：
0 d8 t- D2 K$ J9 x) g* n9 N7 M8. Lee, G. et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461, 402-406 (2009).
0 q% G8 w! v+ A+ ?- a神经疾病：% m; z1 q( s: D
9. Raya, A. et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460, 53-59 (2009).
5 O. Z& X* r6 A- a. x: z' f血液疾病：
1 @) G0 n& F5 v8 Y6 J/ }10. Rashid, S.T. et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. The Journal of Clinical Investigation 120, 3127-3136 (2010).
8 l# F9 h0 M# I, j7 ~6 H Z肝脏疾病：: o; b. D, b; k9 s9 \9 A
11. Moretti, A. et al. Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome. New England Journal of Medicine 363, 1397-1409 (2010).5 f' {2 y9 M# b+ D" W+ i
心脏疾病：
7 Y7 n9 h+ Z2 P+ C1 O7 D12. Ghodsizadeh, A. et al. Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells. Stem Cell Reviews and Reports 6, 622-632 (2010).
( N- T! `: ?/ \, r2 R, R肝脏疾病：
$ j" E" H; }( G5 r, D" ?( r2 X- W, Q
! e$ Z; F! ^, d望细胞海洋多加威望和包包啊~ |
附件: 你需要登录才可以下载或查看附件。没有帐号？注册
-
总评分: 威望 + 72
包包 + 123
查看全部评分
|
发表于 2010-11-5 22:05
发表于 2011-1-5 19:59
