
- 积分
- 2314
- 威望
- 2314
- 包包
- 5399
|

分化但未观察到疾病表型的:" Z" P% B0 ], @
1. Dimos, J.T. et al. Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons. Science 321, 1218-1221 (2008).( v% ]/ h. v3 `
神经疾病:8 k6 I& k% R& c5 r5 J, J
2. Park, I.-H. et al. Disease-Specific Induced Pluripotent Stem Cells. Cell 134, 877-886 (2008). _' ?4 v* x1 }) r
神经疾病:4 K# \& I* E! w
3. Soldner, F. et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell 136, 964-977 (2009).
9 ]% I+ Q9 V: p: \/ [神经疾病:' ]6 [) l3 I) c. P2 |
4. Maehr, R. et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proceedings of the National Academy of Sciences 106, 15768-15773 (2009)./ R5 Z( G Z2 E% ^* l# N& m8 L% y$ W
糖尿病:' d9 ]) x6 w& Q$ b( _
5. Ye, Z. et al. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114, 5473-5480 (2009).3 V4 j. G6 N0 h
血液疾病:- Z/ `* S9 I4 m
6. Yang, J. et al. Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader-Willi syndrome. Journal of Biological Chemistry.
1 b6 w1 O b3 k2 h# \" Agenomic imprinting disorder:) H2 D% N7 g5 O6 K, q
& y! O1 _5 ?. F; y
/ k% |9 _, F% p: o' Y& U* w0 s
成功观察到疾病细胞表型的:# D/ C- T- l3 V
7. Ebert, A.D. et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-280 (2009).4 P* a) P: x) A$ c% Y
神经疾病:
% l! p3 r1 E( p! ?" c8. Lee, G. et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461, 402-406 (2009).
/ M! D( k: Y8 f5 i神经疾病:
0 _+ z N- G; t. l$ E9. Raya, A. et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460, 53-59 (2009).
- q( y' E4 M8 Q( |血液疾病:# S" ~7 {' L; X, `5 P, p0 B2 S# _
10. Rashid, S.T. et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. The Journal of Clinical Investigation 120, 3127-3136 (2010).7 W7 ` x k; B- U- l n
肝脏疾病:+ z% i1 l/ t" x3 I
11. Moretti, A. et al. Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome. New England Journal of Medicine 363, 1397-1409 (2010).
3 ?2 N0 A/ ~0 Y; `4 ?心脏疾病:2 _3 K s/ J" i- T
12. Ghodsizadeh, A. et al. Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells. Stem Cell Reviews and Reports 6, 622-632 (2010).; t! K! i0 [, B' f9 r' L. k
肝脏疾病:
' K7 S6 R2 A( y3 H9 H; y$ Q. J U* ~( c
望细胞海洋多加威望和包包啊~ |
附件: 你需要登录才可以下载或查看附件。没有帐号?注册
-
总评分: 威望 + 72
包包 + 123
查看全部评分
|