2008年Cell杂志的一期不错的干细胞特刊

yusheen

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9 k5 n6 l  ^( b* u( u* Q5 p最近浏览期刊，发现2008年Cell杂志有一期干细胞研究的综述，内容非常全面，感觉对大家非常有用，可以作为教材来研究学习。下载时把文章的补充材料也下下来，供大家学习。0 ], a* H$ ^5 ?
Stem cells have two remarkable abilities: they can self-renew to keep the stem cell pool replenished, and
1 S" O  A& P; \) l& M' c0 z, xthey can differentiate into a wide variety of cell types. This stunning biological duality intrigues not only
: ^* r! S* w$ Z( m3 j9 S, kthose interested in the basic mechanisms of development, differentiation, and reprogramming, but1 A+ W5 D8 Z1 I) g  w: o, F
also those who seek to use stem cells therapeutically to replace lost or damaged tissue. But when did
1 ]+ [4 d# K1 V- R5 S9 i" sthe stem cell revolution start? It was back in the 1960s that two Canadian researchers, Ernest A. McCulloch, f/ y4 b$ {- Q2 ?2 P
and James E. Till, launched the field of stem cell research with their groundbreaking work on the hematopoietic+ X/ r5 l. L! O5 }; T
stem cells of mouse bone marrow. By designing clonogenic assays to measure stem cell differentiation# _% m3 p8 s- _+ w3 q/ P7 f7 o4 z2 s* l
in vitro and serial transplantation assays to study stem cell repopulating ability in vivo, Till and( X. f7 h& i, J4 {% Z' B/ n
McCulloch defined the hallmark characteristics of stem cells.
: I' B. X/ ^$ O/ b3 KThe field of stem cell research has come a long way in 50 years, as we hope will be apparent from this% Y! o( K) z7 C9 n* G5 z' L
year’s Special Review Issue. Our goal in this issue is to highlight the remarkable biological features of5 @% S. ?) n7 U4 i. X' ?) s
stem cells, the molecular pathways that control these characteristics, and the ways in which these enigmatic% p; [# l  ]; N( K. a
cells can be exploited for cell replacement therapy. We would like to thank the many distinguished
5 W7 N( L: W9 D9 {7 O! Y7 M# ]experts who contributed their time and efforts as authors and reviewers to make this special issue on
" E7 {4 l5 V) s' v3 Z6 lstem cells informative, thought-provoking, and timely. We hope that this collection of articles conveys  a- {" y& e, h& Z0 b, J2 N: _$ j7 {
the excitement and promise of stem cell research, as we enter a new era of possibility.

yusheen

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顶一个

chuanbaozang

赞一个

exin11

看看

flydayzhu

look 一下

linlicau

辛苦了，要点包包也能理解。

ayeqiu

下载看看~

ayeqiu

为啥每次都提示“你所在的用户组无法下载或查看附件”…………晕！晕！！晕！！！……

tpwang

回复 ayeqiu 的帖子
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! q8 {  O+ Q9 A0 O你的积分还差9分就可以成为注册会员了，加油。
6 R. `/ p3 K( J% _: j9 j9 Q& {8 V* M, A
参加一些讨论是增加积分的最好办法。

ayeqiu

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5 r' s8 a, C/ S4 m原来是这样啊，谢谢你！