2008年Cell杂志的一期不错的干细胞特刊

yusheen

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: [' M; Z' j3 e; v; g- u最近浏览期刊，发现2008年Cell杂志有一期干细胞研究的综述，内容非常全面，感觉对大家非常有用，可以作为教材来研究学习。下载时把文章的补充材料也下下来，供大家学习。! ]. o' G' q8 e
Stem cells have two remarkable abilities: they can self-renew to keep the stem cell pool replenished, and4 P  @' g/ \, ]
they can differentiate into a wide variety of cell types. This stunning biological duality intrigues not only2 t5 `5 f0 Y! V
those interested in the basic mechanisms of development, differentiation, and reprogramming, but, F/ C* ^  \1 T; j( Q8 ?3 Y
also those who seek to use stem cells therapeutically to replace lost or damaged tissue. But when did
- q' u) R# g0 g* L; k' f& Jthe stem cell revolution start? It was back in the 1960s that two Canadian researchers, Ernest A. McCulloch
5 [& f! i( Z& b9 E4 b" Oand James E. Till, launched the field of stem cell research with their groundbreaking work on the hematopoietic
9 @0 J+ j. }$ Z8 e: N. ^3 h0 Gstem cells of mouse bone marrow. By designing clonogenic assays to measure stem cell differentiation
; B: M! ~" O5 q5 q, Uin vitro and serial transplantation assays to study stem cell repopulating ability in vivo, Till and; Y# S( `) \3 }$ ]' i1 p% [( m7 K
McCulloch defined the hallmark characteristics of stem cells.3 O8 m! R. a9 T! t+ p
The field of stem cell research has come a long way in 50 years, as we hope will be apparent from this" S( O5 K# L5 p/ u! K
year’s Special Review Issue. Our goal in this issue is to highlight the remarkable biological features of+ H0 [; A6 K2 w
stem cells, the molecular pathways that control these characteristics, and the ways in which these enigmatic
) k7 c0 }+ I  y) g6 g: D* f" E( x4 `cells can be exploited for cell replacement therapy. We would like to thank the many distinguished* U* D8 Y$ ?- O& o. i; m
experts who contributed their time and efforts as authors and reviewers to make this special issue on. l- ?6 ^6 q; z, z( R% {8 z! u
stem cells informative, thought-provoking, and timely. We hope that this collection of articles conveys
0 n* K. z4 y% Cthe excitement and promise of stem cell research, as we enter a new era of possibility.

yusheen

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顶一个

chuanbaozang

赞一个

exin11

看看

flydayzhu

look 一下

linlicau

辛苦了，要点包包也能理解。

ayeqiu

下载看看~

ayeqiu

为啥每次都提示“你所在的用户组无法下载或查看附件”…………晕！晕！！晕！！！……

tpwang

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你的积分还差9分就可以成为注册会员了，加油。
) m7 ?) O/ t3 k. Z# ]" q0 M! ?9 H* X& H. a2 l( f2 f
参加一些讨论是增加积分的最好办法。

ayeqiu

回复 tpwang 的帖子9 o: O& W7 C: \: i

2 A0 M# B/ l# l0 K9 j1 S原来是这样啊，谢谢你！